Brain Oligometastasis from Synchronous Uterine Malignancies
- PDF / 333,656 Bytes
- 3 Pages / 595.276 x 790.866 pts Page_size
- 6 Downloads / 142 Views
CASE REPORT
Brain Oligometastasis from Synchronous Uterine Malignancies Varadharajan Vijayakumar 1 & S. Rajasundaram 1 & P. V. Uday Prasad 1 & N. S. Vimalathithan 1 & Shakthi Saravanan 1 & Raksha Venkatesan 1 Received: 8 January 2020 / Accepted: 1 April 2020 # Indian Association of Surgical Oncology 2020
Abstract Synchronous tumors of female genital tract have been uncommonly reported in literature. The most likely scenario would represent a metastatic disease from a primary tumor within the genital tract as the presence of primary synchronous tumors of the genital tract is an extremely rare event. Most primary synchronous tumors tend to involve the endometrium and ovary, while the incidence of synchronous primary tumors involving the uterine cervix and endometrium as documented in a few case series has been around 0.4%. We present a 41-year-old lady with an extremely rare occurrence of synchronous tumors of the uterus with an endometrioid adenocarcinoma of the uterine fundus and a squamous cell carcinoma of the uterine cervix. The patient presented to us with cerebral metastasis, which was successfully managed surgically. Keywords Synchronous uterine malignancy . Cerebral metastasis . Metastatectomy . Cervical cancer . Endometrial cancer
Introduction Cerebral metastasis has been documented in less than 1% of gynecological malignancies with ovarian malignancies metastasizing more frequently than endometrium or the cervix [1]. We present an extremely rare occurrence of synchronous malignancies involving the uterus with an endometrioid adenocarcinoma of the uterus and a squamous cell carcinoma of the uterine cervix, presenting with cerebral oligometastasis. A comprehensive PUBMED search [English Language; 1965–
* Varadharajan Vijayakumar [email protected] S. Rajasundaram [email protected] P. V. Uday Prasad [email protected] N. S. Vimalathithan [email protected] Shakthi Saravanan [email protected] Raksha Venkatesan [email protected] 1
Surgical Oncology, Gleneagles Global Health City, Chennai 600100, India
2015; search terms: synchronous uterine cancers, cerebral metastasis] brought us no reports over synchronous tumors of the genital tract metastasizing to the brain. To the authors’ best knowledge, this is the first reported case with such features.
Case Report A 41-year-old lady was admitted with complaints of sudden onset difficulty in speech and mild clumsiness of the right upper and lower limbs for 20 days. MRI revealed welldefined cystic lesions with rim enhancement in the left fronto-parietal and parieto-occipital regions with significant surrounding edema and areas of hemorrhage within suggestive of metastasis. PET-CT revealed bulky uterus and enhancing endometrial thickening extending up to the lower uterine cavity showing increased metabolic activity with ringenhancing lesions in the brain, consistent with the MRI findings. She was diagnosed as a case of a primary malignancy involving the uterus with cerebral metastasis. A diagnostic hysteroscopy revealed a polyp
Data Loading...
