Buprenorphine overdose
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Somnolence in an infant: case report A 9-month-old boy was hospitalised following accidental ingestion of one buprenorphine/naloxone [Suboxone] 8mg/2mg tablet. He became somnolent and, on admission 30 minutes postingestion, examination revealed mitotic pupils, slow, shallow respiration and depressed mental status. He was treated with naloxone, with a total naloxone dose of 5mg administered before reversal of his somnolence. He remained lethargic with mitotic pupils for approximately 43 hours postingestion. Subsequent urinalysis was positive for buprenorphine. Cho CS, et al. Exploratory buprenorphine ingestion in an infant. Annals of 801041084 Emergency Medicine 48: 109, No. 1, Jul 2006 - USA
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Reactions 15 Jul 2006 No. 1110
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