Carboplatin
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Febrile neutropenia and non-neutropenic fever: 2 case reports In a retrospective study of 33 patients, 2 patients [ages and sexes not stated] were described, among whom one patient developed febrile neutropenia, and the other patient developed non-neutropenic fever during treatment with carboplatin for metastatic seminoma. The patients were hospitalised due to febrile neutropenia and non-neutropenic fever secondary to carboplatin, respectively [dosages, routes, duration of treatments to reactions onsets and outcomes not stated]. Author comment: "There was one admission for febrile neutropenia and one admission for non-neutropenic fevers". "In summary, carboplatin monotherapy is associated with low rates of neutropenic fever compared to cisplatin-based chemotherapy." "Previously reported studies of carboplatin AUC10 monotherapy have described its efficacy. This study reports on the toxicity and deliverability of this regimen." Duncan S, et al. The effect of lowering haematological cut-offs for treatment and blood product support on the deliverability of carboplatin AUC10 in metastatic seminoma. European Urology Supplements 18: 18 abstr. GCT-37, No. 4, Sep 2019. Available from: URL: http://doi.org/10.1016/S1569-9056%2819%2932504-7 803435300 [abstract] - United Kingdom
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Reactions 23 Nov 2019 No. 1780
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