Caveolins and Caveolae Roles in Signaling and Disease Mechanisms

Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membra

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University of Pennsylvania RODOLFO PAOLETTI, University of Milan

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Caveolins and Caveolae Roles in Signaling and Disease Mechanisms   Jean-François Jasmin, PhD Department of Stem Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA Philippe G. Frank, PhD Departments of Cancer Biology, and Stem Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA Michael P. Lisanti, MD, PhD Departments of Cancer Biology, and Stem Cell Biology and Regenerative Medicine Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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