Cellular and Molecular Basis of Mitochondrial Inheritance Mitochondr

This new volume of our successful book series Advances in Anatomy, Embryology and Cell Biology is focused on mitochondrial inheritance in humans and both vertebrate and invertrebate animals including Drosophila, C. elegans, bivalv

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Peter Sutovsky Editor

Cellular and Molecular Basis of Mitochondrial Inheritance Mitochondrial Disease and Fitness

Advances in Anatomy, Embryology and Cell Biology publishes critical reviews and state-ofthe-art surveys on all aspects of anatomy and of developmental, cellular and molecular biology, with a special emphasis on biomedical and translational topics. The series publishes volumes in two different formats: • Contributed volumes, each collecting 5 to 15 focused reviews written by leading experts • Single-authored or multi-authored monographs, providing a comprehensive overview of their topic of research Manuscripts should be addressed to Editor-in-Chief Prof. Dr. P. SUTOVSKY, S141 Animal Science Research Center, Division of Animal Sciences and Department of Obstetrics, Gynecology and Women’s Health, University of Missouri, Columbia, MO, USA e-mail: [email protected] Series Editors Prof. Dr. F. CLASCÁ, Department of Anatomy, Histology and Neurobiology Universidad Autónoma de Madrid, Ave. Arzobispo Morcillo s/n, 28029 Madrid, Spain e-mail: [email protected] Prof. Dr. Z. KMIEC, Department of Histology and Immunology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland e-mail: [email protected] Prof. Dr. H.-W. KORF, Anatomy and Brain Research Center, Department for Anatomy 1, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany e-mail: [email protected] Prof. Dr. M.J. SCHMEISSER, Institute of Microscopic Anatomy and Neurobiology, University Medical Center of the Johannes Gutenberg University, Langenbeckstr 1, 55131 Mainz, Germany e-mail: [email protected] Prof. Dr. B. SINGH, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada e-mail: [email protected] Prof. Dr. J.-P. TIMMERMANS, Laboratory of Cell Biology and Histology/Core Facility Biomedical Microscopic Imaging, Department of Veterinary Sciences, University of Antwerp, Drie Eiken Campus, Universiteitsplein 1, 2610 Wilrijk, Belgium e-mail: [email protected]

231 Advances in Anatomy, Embryology and Cell Biology

Editor-in-Chief P. Sutovsky

Series Editors F. Clascá • Z. Kmiec • H.-W. Korf • M.J. Schmeisser • B. Singh • J.-P. Timmermans More information about this series at http://www.springer.com/series/102

Peter Sutovsky Editor

Cellular and Molecular Basis of Mitochondrial Inheritance Mitochondrial Disease and Fitness

Editor Peter Sutovsky Division of Animal Sciences and Department of Obstetrics, Gynecology and Women’s Health University of Missouri Columbia, MO, USA

ISSN 0301-5556 ISSN 2192-7065 (electronic) Advances in Anatomy, Embryology and Cell Biology ISBN 978-3-030-04569-2 ISBN 978-3-030-04570-8 (eBook) https://doi.org/10.1007/978-3-030-04570-8 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproducti