Cellular Physiology and Metabolism of Physical Exercise
The book covers areas of cellular physiology and metabolism that are of interest to scientists involved in research in diabetes and metabolic diseases. Some chapters of the book are specifically research-oriented, as all the authors are actively practicin
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Livio Luzi Editor
Cellular Physiology and Metabolism of Physical Exercise
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Editor Livio Luzi Department of Sport Sciences, Nutrition and Health University of Milan Milan, Italy
The contents of the book are partially based on Biologia cellulare nell’esercizio fisico. Livio Luzi © Springer-Verlag Italia 2010
ISBN 978-88-470-2417-5
e-ISBN 978-88-470-2418-2
DOI 10.1007/978-88-470-2418-2 Springer Milan Heidelberg New York Dordrecht London Library of Congress Control Number: 2011940031 © Springer-Verlag Italia 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in databanks. Duplication of this publication or parts thereof is permitted only under the provisions of the Italian Copyright Law in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the Italian Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. 987654321 Cover design: Ikona S.r.l., Milano Typesetting: Ikona S.r.l., Milano Printing and binding: Printer Trento S.r.l., Trento Printed in Italy Springer-Verlag Italia S.r.l. – Via Decembrio 28 – I-20137 Milan Springer is a part of Springer Science+Business Media
2012 2013 2014
Dedicated to my father, Mario, who died on May 31, 2011
Preface
Cellular Physiology and Metabolism of Physical Exercise deals with several areas of science, including evolution. Physical inactivity is one of the leading causes of death in industrialized countries. Accordingly, intensive research has been devoted to studies of the regulation of muscle physiology and contraction. In this volume, these topics are particularly up to date and thoroughly debated. The aim of this book is to furnish both a basic and an advanced scientific portrait of the cellular physiology of skeletal muscle cells. Basic information includes an overview of muscle cell morphology, biochemistry, molecular biology, and physiology, with special emphasis on the cell membrane, energy metabolism, and cell contraction. Particularly innovative are the chapters dealing with methodologies to study, both invasively (muscle biopsies) and non-invasively (NMR-spectroscopy, mathematical modeling), intracellular metabolism and physiology. A specific chapter is dedicated to a new frontier of research in the field of sport sciences, namely, the possibility of correlating specific DNA polymorphisms and athletic
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