Chronic Lymphocytic Leukemia

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long ti

  • PDF / 3,412,781 Bytes
  • 191 Pages / 439.378 x 666.139 pts Page_size
  • 57 Downloads / 205 Views

DOWNLOAD

REPORT


Editors R. W. Compans, Atlanta/Georgia M. D. Cooper, Birmingham/Alabama T. Honjo, Kyoto · H. Koprowski, Philadelphia/Pennsylvania F. Melchers, Basel · M. B. A. Oldstone, La Jolla/California S. Olsnes, Oslo · M. Potter, Bethesda/Maryland P. K. Vogt, La Jolla/California · H. Wagner, Munich

F. Caligaris-Cappio and R. Dalla-Favera (Eds.)

Chronic Lymphocytic Leukemia With 35 Figures and 5 Tables

123

Federico Caligaris-Cappio Department of Oncology IRCCS San Raffaele Università Vita-Salute San Raffaele Via Olgettina 60 20132 Milan Italy e-mail: [email protected] Riccardo Dalla-Favera, MD Institute of Genetics Columbia University 1150 St. Nicolas Avenue New York, NY 10032 USA e-mail: [email protected]

Library of Congress Catalog Number 72-152360 ISSN 0070-217X ISBN-10 3-540-25279-7 Springer Berlin Heidelberg New York ISBN-13 978-3-540-25279-5 Springer Berlin Heidelberg New York This work is subject to copyright. All rights reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September, 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springeronline.com © Springer-Verlag Berlin Heidelberg 2005 Printed in Germany The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Editor: Simon Rallison, Heidelberg Desk editor: Anne Clauss, Heidelberg Production editor: Nadja Kroke, Leipzig Cover design: design & production GmbH, Heidelberg Typesetting: LE-TEX Jelonek, Schmidt & Vöckler GbR, Leipzig Printed on acid-free paper SPIN 11017387 27/3150/YL – 5 4 3 2 1 0

Preface

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B cell chronic lymphoid malignancies. For a long time the Cinderella of lymphoid malignancies, CLL has now become the focus of major interest, and an increasing number of investigators from different areas including genetics, molecular biology and basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects that aim at translating the exciting developments of basic science into effective new approaches to the patient. Many re