Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses
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RESEARCH ARTICLE
Open Access
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses Nazlisadat Seyed Khoei1, Mazda Jenab2, Neil Murphy2, Barbara L. Banbury3, Robert Carreras-Torres4, Vivian Viallon5, Tilman Kühn6, Bas Bueno-de-Mesquita7,8,9,10, Krasimira Aleksandrova11, Amanda J. Cross9, Elisabete Weiderpass12, Magdalena Stepien2, Andrew Bulmer13,14, Anne Tjønneland15,16, Marie-Christine Boutron-Ruault17,18, Gianluca Severi17,18, Franck Carbonnel17,18,19, Verena Katzke6, Heiner Boeing20, Manuela M. Bergmann20, Antonia Trichopoulou21, Anna Karakatsani21,22, Georgia Martimianaki21, Domenico Palli23, Giovanna Tagliabue24, Salvatore Panico25, Rosario Tumino26, Carlotta Sacerdote27, Guri Skeie28,29, Susana Merino30, Catalina Bonet31, Miguel Rodríguez-Barranco32,33, Leire Gil34, Maria-Dolores Chirlaque35,33, Eva Ardanaz36,37,33, Robin Myte38, Johan Hultdin39, Aurora Perez-Cornago40, Dagfinn Aune9,41,42, Konstantinos K. Tsilidis9,43, Demetrius Albanes44, John A. Baron45, Sonja I. Berndt44, Stéphane Bézieau46, Hermann Brenner47,48,49, Peter T. Campbell50, Graham Casey51, Andrew T. Chan52,53,54,55,56,57, Jenny Chang-Claude6,58, Stephen J. Chanock44, Michelle Cotterchio59,60, Steven Gallinger61, Stephen B. Gruber62, Robert W. Haile63, Jochen Hampe64, Michael Hoffmeister47, John L. Hopper65,66, Li Hsu3,67, Jeroen R. Huyghe3, Mark A. Jenkins65, Amit D. Joshi56,54, Ellen Kampman68, Susanna C. Larsson69, Loic Le Marchand70, Christopher I. Li3, Li Li71, Annika Lindblom72,73, Noralane M. Lindor74, Vicente Martín33,75, Victor Moreno4,31,33,76, Polly A. Newcomb3,77, Kenneth Offit78,79, Shuji Ogino80,81,56,55, Patrick S. Parfrey82, Paul D. P. Pharoah83, Gad Rennert84,85,86, Lori C. Sakoda87,3, Clemens Schafmayer88, Stephanie L. Schmit89,62, Robert E. Schoen90, Martha L. Slattery91, Stephen N. Thibodeau92, Cornelia M. Ulrich93, Franzel J. B. van Duijnhoven68, Korbinian Weigl47,49,94, Stephanie J. Weinstein44, Emily White3,77, Alicja Wolk69, Michael O. Woods95, Anna H. Wu96, Xuehong Zhang53, Pietro Ferrari5, Gabriele Anton97, Annette Peters97, Ulrike Peters3,77, Marc J. Gunter2, Karl-Heinz Wagner1† and Heinz Freisling5*†
* Correspondence: [email protected] † Karl-Heinz Wagner and Heinz Freisling shared last authorship. 5 Nutritional Methodology and Biostatistics Group, Section of Nutrition and Metabolism, International Agency for Research on Cancer (IARC-WHO), 150 cours Albert Thomas, 69372 Lyon CEDEX 08, France Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indi
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