Circulating Tumor Cells
This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications a
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Richard J. Cote Ram H. Datar Editors
Circulating Tumor Cells Advances in Basic Science and Clinical Applications
Current Cancer Research
Series Editor: Wafik El-Deiry
More information about this series at http://www.springer.com/series/7892
Richard J. Cote • Ram H. Datar Editors
Circulating Tumor Cells Advances in Basic Science and Clinical Applications
Editors Richard J. Cote University of Miami Jackson Memorial Hospital Miami, FL, USA
Ram H. Datar University of Miami Miami, FL, USA
ISSN 2199-2584 ISSN 2199-2592 (electronic) Current Cancer Research ISBN 978-1-4939-3361-7 ISBN 978-1-4939-3363-1 (eBook) DOI 10.1007/978-1-4939-3363-1 Library of Congress Control Number: 2015959021 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
Metastasis is the process that defines cancer. Studies in understanding circulating tumor cells have been at the forefront of efforts to favorably impact the morbidity and mortality due to metastatic spread of the cancer. In the making of this book, an effort made possible by the world’s leading investigators, it is important to remember and recognize those who we aim to cure. We dedicate this volume to those countless cancer sufferers across the world, and hope that this sharing of knowledge will move us closer to alleviating this emperor of maladies. This book is dedicated to mentors and colleagues. Dr. Lloyd J. Old, Dr. Edward J. Beattie, and Dr. A. Munro Neville are entirely responsible for any contribution I may have made to this field. Dr. Clive R. Taylor allowed me to pursue these studies when most of the scientific community considered micrometastases and CTC to be of no consequence. And Dr. Ram H. Datar has been my longtime collaborator and friend. I am also deeply grateful to my family, Annie, Nick, Juliet, and Gr
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