Clinical characteristics and risk factors of severe respiratory syncytial virus-associated acute lower respiratory tract
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Clinical characteristics and risk factors of severe respiratory syncytial virus-associated acute lower respiratory tract infections in hospitalized infants Xiao-Bo Zhang, Li-Juan Liu, Li-Ling Qian, Gao-Li Jiang, Chuan-Kai Wang, Pin Jia, Peng Shi, Jin Xu, Li-Bo Wang Shanghai, China
Brief report
Background: To investigate the clinical characteristics and analyze risk factors for severe respiratory syncytial virus (RSV) infection in hospitalized infants with acute lower respiratory tract infections (ALRIs). Methods: A retrospective review of the medical records of infants with RSV-associated ALRIs between March 1st, 2011 and February 29th, 2012 was conducted. Subjects were followed up over the phone or by outpatient visit six and twelve months after discharge. Results: Among 913 RSV-associated ALRIs infants, 288 (31.5%) had severe infections, which accounted for 4.2% of hospitalized children. The hospital RSV mortality rate was 1.0%. The proportions of cases with tachypnea, apnea, cyanosis, and fine rales were significantly higher in the severe ALRIs group (all P
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