Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients
- PDF / 1,024,509 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 18 Downloads / 218 Views
ORIGINAL PAPER
Clinical characteristics of pediatric hidradenitis suppurativa: a cross‑sectional multicenter study of 140 patients Peter Theut Riis1,2 · Ditte Marie Saunte1,2 · Viktoria Sigsgaard1,2 · Axel Patrice Villani3,4 · Philippe Guillem3 · José C. Pascual5 · Naomi N. Kappe6 · Annika M. J. D. Vanlaerhoven6 · Hessel H. van der Zee6 · Errol P. Prens6 · Moetaz El‑Domyati7 · Hossam Abdel‑Wahab7 · Nayera Moftah8 · Rania Abdelghani8,9 · Eugenia Agut‑Busquet25,26 · Jorge Romaní10 · Carol Hlela11 · Lerinza van den Worm11 · Vincenzo Bettoli12 · Giada Calamo12 · Mehmet Ali Gürer13 · Burcu Beksaç13 · Lukasz Matusiak14 · Amelia Glowaczewska14 · Jacek C. Szepietowski14 · Lennart Emtestam15 · Jan Lapins15 · Hassan Riad Kottb16 · Mohammad Fatani17 · Lisa Weibel18,19 · Martin Theiler18,19 · Maïa Delage‑Toriel20 · Thi Thanh Hong Lam20 · Aude Nassif20 · Pierre‑Andre Becherel21 · Mateja Dolenc‑Voljc22 · Nejib Doss23 · Dorra Bouazzi1,2 · Farida Benhadou24 · Veronique del Marmol24 · Gregor B. E. Jemec1,2 Received: 28 September 2019 / Accepted: 26 February 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases. Keywords Hidradenitis suppurativa · Children · Pediatric · Acne inversa
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Patients recurrently develop painful nodules in the intertriginous regions. The nodules progress to abscesses that heal with scars, potentially forming cutaneous tunnels P.T.R., D.M.S., V.S., A.P.V., J.C.P., D.B., F.B., V.M. and G.B.E.J.: European Reference Network for Rare and Complex Diseases of the Skin (ERN-Skin) member. Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00403-020-02053-6) contains supplementary material, which is available to authorized users. * Peter Theut Riis pmik@regi
Data Loading...
