Clinical efficacy and safety of bone cement combined with radiofrequency ablation in the treatment of spinal metastases
- PDF / 510,932 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 20 Downloads / 182 Views
TECHNICAL ADVANCE
Open Access
Clinical efficacy and safety of bone cement combined with radiofrequency ablation in the treatment of spinal metastases Nanning Lv1†, Rui Geng2†, Feng Ling3†, Zhangzhe Zhou4* and Mingming Liu1*
Abstract Background: To investigate the clinical efficacy and safety of bone cement combined with radiofrequency ablation (RFA) in the treatment of spinal metastases. Methods: The medical records of patients with spinal metastatic tumor admitted to our hospital from January 2016 to December 2018 were retrospectively analyzed. Based on different surgical methods, the patients were divided into groups A (treated with RFA combined with bone cement) and B (treated with bone cement only). Group A included 35 patients with 47 segments of diseased vertebral bodies. Group B consisted of 52 patients with 78 vertebral segments. Pain, quality of life score, vertebra height, bone cement leakage, postoperative tumor recurrence, and complications were assessed 3 days and 1 and 6 months after surgery. Results: All the patients had smooth operation without paraplegia, spinal cord injury, and perioperative death. Visual analogue scales (VAS) and Oswestry Disability Index (ODI) scores of the two groups significantly improved 3 days and 1 month after surgery compared with those before surgery (P < 0.05), but no significant difference was observed between the two groups (P > 0.05). Six months after surgery, the VAS and ODI scores of patients in group A were lower than those in group B, with statistically significant differences (P < 0.05). The postoperative vertebral body height of the two groups significantly increased compared with that before surgery, and the difference was statistically significant (P < 0.05). Meanwhile, no significant difference was observed between the two groups (P > 0.05). Postoperative bone cement permeability in group A was 6.4%, and postoperative tumor recurrence rate was 11.4%. The permeability of bone cement in group B was 20.5%, and the tumor recurrence rate was 30.8%. The bone cement permeability and tumor recurrence rate in group A were lower than those in group B, with statistically significant differences (P < 0.05). Conclusions: Bone cement combined with RFA for the treatment of spinal metastases can achieve good efficacy, desirable analgesic effect, low incidence of complications, small surgical trauma, and high safety. The proposed method has the value of clinical popularization and application. Keywords: Percutaneous kyphoplasty, Bone cement, Radio frequency ablation, Spinal metastases
* Correspondence: [email protected]; [email protected] † Nanning Lv, Rui Geng and Feng Ling contributed equally to this work. 4 Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou 215006, Jiangsu, China 1 Department of Orthopedic Surgery, The Second People’s Hospital of Lianyungang, 41 Hailian East Street, Lianyungang 222003, Jiangsu, China Full list of author information is available at the end of the article © The Author(s). 2
Data Loading...
