Clinical Features of COVID-19 Patients in Xiaogan City
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COVID-19
Clinical Features of COVID-19 Patients in Xiaogan City Gong Feng 1 & Wan-Qiang Huang 2 & Man-Ling Liu 1 & Si-Ceng Lin 1 & Xiao-Zhou Zhang 2 & Yan Zhang 3 & Xiao-Qing He 4 & Jun-Lin Liu 1 & Zi-Jun Chen 5 & Zi-Kai Guo 1 & Jie Gao 1 & Cheng-Zi Yao 1 & Na He 6 & Qin-Qin Yan 1 & Man Mi 1 Accepted: 17 August 2020 # Springer Nature Switzerland AG 2020
Abstract On February 6, 2020, Xiaogan City became the second most seriously affected city with coronavirus disease 2019 (COVID-19), outside Wuhan district, Hubei Province, China. The objectives are to study the clinical features of COVID-19 patients and assess the relationship between the severity of COVID-19, age, and C-reactive protein (CRP) levels. The retrospective data of 134 COVID-19 patients hospitalized in 3 hospitals of Xiaogan City, between February 1 and March 1, 2020, was collected. This study documented COVID-19 patients. Clinical data in terms of body temperature, history of travel, and direct contact with COVID-19 patients, and incubation period was collected. Out of the 134 patients, only 5 required intensive care. Moreover, 2 patients succumbed during this period. The median age of patients was 45 (33– 56) years. The most common symptoms at the onset of disease were fever (66.4%), cough (33, 6%), and sore throat (14.7%). Amongst the medicines used, antiviral agents (92.3%) followed by the traditional Chinese medicine (89.5%) were most commonly used. In both the crude and adjusted (I to III) models, odds ratio and its 95% confidence interval for both age and CRP levels were > 1. Moreover, the smooth curve fitting graph reflected that the severity of COVID-19 was positively correlated with both age and CRP levels (all P value < 0.05). The signs and symptoms of COVID-19 patients were fairly moderate. The health care professionals treating the COVID-19 patients should be aware of the increased likelihood of progression to severe COVID-19 in elderly patients and those with high CRP levels. Keywords Coronavirus disease 2019 . C-reactive protein . Case series
Introduction Wan-Qiang Huang, Man-Ling Liu, Si-Ceng Lin, Xiao-Zhou Zhang, Yan Zhang, Xiao-Qing He and Jun-Lin Liu contributed equally to this work. This article is part of the Topical Collection on Covid-19 * Na He [email protected] * Qin-Qin Yan [email protected] * Man Mi [email protected] 1
Xi’an Medical University, Xi’an, China
2
Xiaogan Central Hospital, Xiaogan, China
3
Department of respiratory medicine, Tangdu Hospital Affiliated to Air Force Military Medical University, Xi’an, China
4
Chang’an University, Xi’an, China
5
Pufang Hospital, Chibi, China
6
Department of Gastroenterology, The First Affiliated Hospital of Xi’an Medical University, Xi’an, China
Coronavirus disease 2019 (COVID-19), resulting from an infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a serious threat to global public health [1, 2]. On February 6, 2020, Xiaogan City became the second most seriously affected city, outside Wuhan, Hubei Province, China, by COVID-19
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