Clinical, procedural and long-term outcome of ischemic VT ablation in patients with previous anterior versus inferior my
- PDF / 808,156 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 76 Downloads / 179 Views
ORIGINAL PAPER
Clinical, procedural and long‑term outcome of ischemic VT ablation in patients with previous anterior versus inferior myocardial infarction Kristina Wasmer1 · Holger Reinecke2 · Marius Heitmann1 · Dirk G. Dechering1 · Florian Reinke1 · Philipp S. Lange1 · Gerrit Frommeyer1 · Simon Kochhäuser1 · Patrick Leitz1 · Lars Eckardt1 · Julia Köbe1 Received: 30 May 2019 / Accepted: 19 February 2020 © The Author(s) 2020
Abstract Background Outcome of ischemic VT ablation may differ between patients with previous myocardial infarction (MI) in relation to infarct localization. Methods We analyzed procedural data, acute and long-term outcomes of 152 consecutive patients (139 men, mean age 67 ± 9 years) with previous anterior or inferior MI who underwent ischemic VT ablation at our institution between January 2010 and October 2015. Results More patients had a history of inferior MI (58%). Mean ejection fraction was significantly lower in anterior MI patients (28 ± 10% vs. 34 ± 10%, p 6 h). Acute ablation outcome was analyzed separately as (1) complete success with no inducible VT, (2) partial success if clinical VT is no longer inducible but non-clinical VT is still inducible, or (3) unsuccessful if the clinical VT was still inducible. ICD were interrogated and reprogrammed after the procedure and pericardial effusion was excluded by echocardiography. Amiodarone was started, continued or discontinued after VT ablation is at the discretion of the treating physician.
and ICD therapies. For deceased patients, date of death was documented and cause of death was classified as cardiac (arrhythmic/non-arrhythmic), non-cardiac or unknown.
Statistical analysis The cohort was divided into two subgroups according to the location of MI. Categorical variables are presented as absolute numbers (n) and percentages (%) of the total numbers for each subgroup; statistical comparisons for these were made by the Chi-squared test. Continuous variables were tested by the ANOVA-F test. The impact of the infarct localization on cardiovascular and overall mortality was tested by multivariable Cox regression models adjusted for the number of affected coronary vessels, previous bypass surgery, NYHA class, diabetes, and amiodarone use. Results were displayed as cumulative event curves. The impact of infarct localization on VT recurrence was displayed by Kaplan–Meier model as cumulative event curve. All tests performed were two-sided, and p values of
Data Loading...
