Comparison of real time 3-dimensional echocardiography with cardiovascular magnetic resonance for left ventricular volum
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BioMed Central
Open Access
Poster presentation
Comparison of real time 3-dimensional echocardiography with cardiovascular magnetic resonance for left ventricular volumetric assessment - a real world study Christopher A Miller*, Keith A Pearce, Peter Jordan, Simon G Ray and Matthias Schmitt Address: University Hospital of South Manchester, Manchester, UK * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P243
doi:10.1186/1532-429X-12-S1-P243
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/P243 © 2010 Miller et al; licensee BioMed Central Ltd.
Study objective
Results
To assess the accuracy and reproducibility of real time 3dimensional echocardiography (RT3DE) for left ventricular (LV) volumetric assessment in consecutive, unselected patients.
Only 13 patients (22%) were deemed to have good RT3DE image quality by both observers. In these patients, RT3DE measurement of EF correlated highly with CMR (mean+standard deviation -2.0 + 4%, r = 0.97, Bland-Altman 95% levels of agreement (BA) -9 to 5%). LV volumes were underestimated by RT3DE (end diastolic volume (EDV) -26 + 23 mls, end systolic volume (ESV) -10 + 19 mls) in keeping with findings from other studies. Interobserver reproducibility for measurement of EF was high (1.2+ 3%, r = 0.98, BA -5 to 7%); as was intra-observer reproducibility (0.1 + 2%, r = 0.99, BA -4 to 4%) (Table 1). 29 patients had adequate RT3DE image quality. In these patients, correlation of RT3DE and CMR measurement of EF was significantly lower (-0.5 + 9, r = 0.82, BA -19 to 18%). LV volumes were underestimated to a greater degree (EDV -39 + 31 mls, ESV -11 + 31 mls) and interobserver (-1.2 + 6%, r = 0.84, BA -13 to 10%) and intraobserver reproducibility (0.5 + 4, r = 0.97, -7 to 8%) were also considerably lower (Table). RT3DE image quality was deemed non-analysable in 18 patients (30%), with inadequate visualisation of the anterior wall alone being responsible in 10 (56%).
Introduction The accuracy and reproducibility of RT3DE for LV volumetric assessment has been demonstrated in a number of clinical trials. We aimed to assess the 'real-world' accuracy and reproducibility of RT3DE in consecutive, unselected patients.
Methods Sixty patients undergoing clinically indicated cardiac magnetic resonance imaging (CMR) also underwent RT3DE. CMR images were obtained using a 1.5 T scanner (Siemens Avanto, Germany) equipped with a 32-channel surface coil. RT3DE images were obtained using an IE33 scanner (Philips, USA). LV volumes and ejection fraction (EF) were measured by 2 independent observers for both modalities. RT3DE measurements were compared to those obtained by CMR. Inter-observer reproducibilit
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