Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcin
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RESEARCH ARTICLE
Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma Na Qin1,*, Yuancheng Li1,*, Cheng Wang1,2,3, Meng Zhu1,4, Juncheng Dai1,2,4,5, Tongtong Hong1, Demetrius Albanes6, Stephen Lam7, Adonina Tardon8, Chu Chen9, Gary Goodman10, Stig E. Bojesen11, Maria Teresa Landi12, Mattias Johansson13, Angela Risch14, H-Erich Wichmann15, Heike Bickeboller16, Gadi Rennert17, Susanne Arnold18, Paul Brennan13, John K. Field19, Sanjay Shete20, Loic Le Marchand21, Olle Melander22, Hans Brunnstrom22, Geoffrey Liu23, Rayjean J. Hung24, Angeline Andrew25, Lambertus A. Kiemeney26, Shan Zienolddiny27, Kjell Grankvist28, Mikael Johansson29, Neil Caporaso30, Penella Woll31, Philip Lazarus32, Matthew B. Schabath33, Melinda C. Aldrich34, Victoria L. Stevens35, Guangfu Jin1,2,4,5, David C. Christiani5,36, Zhibin Hu1,2,5, Christopher I. Amos37, Hongxia Ma ( )1,2,4,5, Hongbing Shen ( )1,2,4,5
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Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China; State Key Laboratory of Reproductive Medicine, Center for Global Health, Nanjing Medical University, Nanjing 211166, China; 3 Department of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China; 4 Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing 211166, China; 5China International Cooperation Center for Environment and Human Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China; 6Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-9304, USA; 7Department of Integrative Oncology, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada; 8Faculty of Medicine, University of Oviedo and CIBERESP, Oviedo 33006, Spain; 9Program in Epidemiology, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA; 10Public Health Sciences Division, Swedish Cancer Institute, Seattle, WA 98026, USA; 11Department of Clinical Biochemistry, Copenhagen University Hospital, Copenhagen DK-1017, Denmark; 12National Cancer Institute, Bethesda, MD 20892-9304, USA; 13Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon 69372, France; 14Cancer Center Cluster Salzburg at PLUS, Department of Molecular Biology, University of Salzburg, Heidelberg 5020, Austria; 15Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig Maximilians University, Munich, Bavaria 80539, Germany; 16Department of Genetic Epidemiology, University Medical Center Goettingen, Goettingen 37075, Germany; 17 Technion Faculty of Medicine, Carmel Medical Center, Haifa 3448516, Israel; 18Markey Cancer Center, University of Kentucky, Lexington, KY 40506-0054, USA; 19Department of Molecular and Clinical Cancer Medicine, Roy Castle Lung Cancer R
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