Congress of neurological surgeons systematic review and evidence-based clinical practice parameter guidelines for the tr
- PDF / 489,853 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 63 Downloads / 183 Views
INTRODUCTION AND METHODS
Congress of neurological surgeons systematic review and evidence‑based clinical practice parameter guidelines for the treatment of adults with newly diagnosed glioblastoma: Introduction and Methods Jeffrey J. Olson1 · Timothy C. Ryken2 Received: 12 July 2020 / Accepted: 7 August 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Purpose This is an update of the evidence-based guideline for management of newly diagnosed glioblastomas sponsored by the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) initially published in 2008. The objective is to update evidence-based management of newly diagnosed glioblastomas over all commonly used diagnostic and treatment modalities in regularly encountered clinical situations. Methods A multidisciplinary writing group was assembled to create documents related to imaging, cytoreductive surgery, neuropathology, radiation therapy, chemotherapy and emerging developments. Questions from the prior set of guidelines, and new and modified questions were used to guide a search of the scientific literature since the last guideline search was completed in June 2005. Citations were screened, classified and used as evidence to create recommendations addressing the questions in a manner that was directly linked to this evidence. Results The sixteen writers produced 34 questions resulting in eight Level I recommendations, eleven Level II recommendations, and 27 Level II recommendations across all the topics. In some instances, insufficient data was available to answer all or part of a question and this is stated and explained. Conclusions This series of guidelines is based upon relevant evidence in the literature related to the management of newly diagnosed glioblastomas. They set a benchmark for the management of this disease while highlighting key areas of weakness in our knowledge and suggest directions for future basic and clinical research to improve evidence quality and recommendation strength. Keywords Glioblastoma · Therapy · Guidelines
Introduction Background and rationale Sponsored by the American Association of Neurological Surgeons and Congress of Neurological Surgeons Joint Section on Tumors. Reviewed for evidence-based integrity and endorsed by the American Association of Neurological Surgeons and Congress of Neurological Surgeons. * Jeffrey J. Olson [email protected] 1
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
Section of Neurosurgery, Dartmouth University, Hanover, NH, USA
2
In 2008 guidelines on the management of newly diagnosed glioblastoma were published and endorsed by the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) [1–6]. A component of that set of guidelines was recognition that updates would eventually be necessary so as to allow the recommendations to be modified to stay abreast of advances in the care and management of newly diagnosed glioblastomas. This docu
Data Loading...
