Controlled Gene Delivery Systems for Articular Cartilage Repair

Delivery of efficient and safe gene transfer vectors capable of achieving appropriate levels of therapeutic gene expression into the target place is a very valuable strategy for articular cartilage repair. Diverse nonviral and viral gene vehicles have bee

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Anuj Tripathi Jose Savio Melo Editors

Advances in Biomaterials for Biomedical Applications

Advanced Structured Materials Volume 66

Series editors Andreas Öchsner, Southport Queensland, Australia Lucas F.M. da Silva, Porto, Portugal Holm Altenbach, Magdeburg, Germany

More information about this series at http://www.springer.com/series/8611

Anuj Tripathi Jose Savio Melo •

Editors

Advances in Biomaterials for Biomedical Applications

123

Editors Anuj Tripathi Nuclear Agriculture and Biotechnology Division Bhabha Atomic Research Centre Mumbai, Maharashtra India

ISSN 1869-8433 Advanced Structured Materials ISBN 978-981-10-3327-8 DOI 10.1007/978-981-10-3328-5

Jose Savio Melo Nuclear Agriculture and Biotechnology Division Bhabha Atomic Research Centre Mumbai, Maharashtra India

ISSN 1869-8441

(electronic)

ISBN 978-981-10-3328-5

(eBook)

Library of Congress Control Number: 2016960027 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #22-06/08 Gateway East, Singapore 189721, Singapore

Preface

A meteoric scientific and technological revolution in biomedicine is underway and is ruling by advanced biomaterials. A number of factors involved in biomaterials’ advancement complement each other. Science of materials, synthesis procedures, and analytical contrivance are some of the major factors that have transformed over a period of time, thus popularizing the biomaterials for their advanced biomedical applications. Much of revolution in biomaterials is fundamental in nature; however, advances are often based on the new and extended understanding of basic principles of biomaterials along with its applications. Biomaterials are a class of materials that are intended for applications in the biomedical field without being biologically vulnerable. Amon