Correlation of Aortic Intima-Media Thickness With Birthweight in Healthy Term and Near Term Neonates

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Correlation of Aortic Intima-Media Thickness With Birthweight in Healthy Term and Near Term Neonates RANGANATHA ASHOK DEVARANAVADAGI1, VIJAY HALAGAPPANAVAR VAMADEVAPPA2 AND GIRISH GURURAJA1 From Departments of 1Pediatrics and 2Radiology, Apollo BGS hospital, Mysore, Karnataka, India.

Correspondence to: Dr Girish Gururaja, Consultant Neonatologist, Apollo BGS hospital, Adichunchanagiri road, Kuvempunagar, Mysore, Karnataka 570 023, India. [email protected]. Submitted: August 19, 2019; Initial review: November 14, 2019; Accepted: March 14, 2020.

Objectives: The primary objective was to correlate aortic intima-media thickness (aIMT) measured at L1-L2 with birth weight in neonates born at ≥35 week of gestation. The secondary objective was to compare aIMT in small for gestational age (SGA) and appropriate for gestational age (AGA) babies in this cohort. Methods: Prospective observational study enrolling 200 newborns. aIMT was measured on day 3 of life using 10-12 MHz ultrasound probe. Relevant maternal and baby details were collected and analyzed. Results: Mean (SD) aIMT was 0.43 (0.15) mm. There was a negative correlation between aIMT and birthweight (r= -0.64). Mean (SD) aIMT in AGA was significantly lesser than in SGA babies (0.36 (0.11) vs. 0.64 (0.08) mm; P

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