Dental Stem Cells
This book explores dental stem cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine.
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Fikrettin Şahin Ayşegül Doğan Selami Demirci Editors
Dental Stem Cells
Stem Cell Biology and Regenerative Medicine
Series Editor Kursad Turksen, Ph.D. [email protected]
More information about this series at http://www.springer.com/series/7896
Fikrettin Şahin • Ayşegül Doğan Selami Demirci Editors
Dental Stem Cells
Editors Fikrettin Şahin Genetics and Bioengineering Department Yeditepe University Istanbul, Turkey
Ayşegül Doğan Genetics and Bioengineering Department Yeditepe University Istanbul, Turkey
Selami Demirci Genetics and Bioengineering Department Yeditepe University Istanbul, Turkey
ISSN 2196-8985 ISSN 2196-8993 (electronic) Stem Cell Biology and Regenerative Medicine ISBN 978-3-319-28945-8 ISBN 978-3-319-28947-2 (eBook) DOI 10.1007/978-3-319-28947-2 Library of Congress Control Number: 2016931885 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
Stem cells are a class of undifferentiated master cells that have robust self-renewal kinetic and differentiation potential into many specialized cell types in the body. Stem cell research has been a field of great clinical interest with immense possibilities of using the stem cells to replace, restore, or enhance the biological function of damaged tissues and organs due to accidents, diseases, and/or developmental defects. Recent studies have demonstrated that mesenchymal stem cells (MSCs) are found in various tissues in an adult organism. MSCs derived from teeth and supporting tissues, called dental stem cells (DSCs), have been mainly characterized into five different cell types including dental pulp stem cells (DPSCs), dental follicle stem cells (DFSCs), periodontal ligament stem cells (PDLSCs), stem cells from human exfoliated deciduous teeth (SHEDs), and stem cells from the apical papilla
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