Deposition of biocompatible nano biocomposite layers on 316L SS surface for bone implant applications
- PDF / 1,697,859 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 21 Downloads / 181 Views
ORIGINAL PAPER
Deposition of biocompatible nano biocomposite layers on 316L SS surface for bone implant applications Ramalingam Manonmani1 Received: 12 August 2020 / Accepted: 12 October 2020 © Iranian Chemical Society 2020
Abstract High osteoblast proliferation-based bioactive corrosion resistance of nano biocomposite (nanoHAP: nanoTiO2) coatings on 316L stainless steel (316L SS) is developed by electrophoretic deposition process (EPD) followed by vacuum sintering, and the surfaces were characterized. The electrochemical performances of the nano biocomposite coated samples were evaluated in Hank’s solution. The uniform distribution of coatings and the formation of a stable nano biocomposite–metal interface with improved corrosion resistance were obtained at a constant potential of 30 V and 1 min. Cytotoxicity and cell culture studies were carried out with MC3T3-E1 osteoblast cell indicating non-toxicity and a higher level of cell proliferation of coated samples. These studies proved the improved corrosion resistance with enhanced cell attachment and proliferation on the nano biocomposite coated samples thus producing it an ideal candidate for biomedical application. Keywords Biocomposite · Sintering · Corrosion resistance · Coating · Interface · Cell proliferation
Introduction Metals, ceramics, polymers, and composites are being greatly engaged to replace bones in the surgical treatment of the injured parts [1]. Among various materials available in the market, metallic implant materials and alloys are widely used for load-bearing applications due to excellent corrosion resistance and mechanical strength. 316L stainless steel (316L SS) implants highly attractive in the medical field due to biocompatibility, excellent fabrication properties, high corrosion resistance, broader availability, and low cost [2]. Today, the focus on reducing expenditure in public health services is of enormous importance and thus stainless steel is widely used for human body implants. Although stainless steels are highly corrosion resistant in many environments, localized corrosion can take place after long periods of implantation in the human body. The corrosion products released could be very injurious to human health and create toxicity to the neighboring cells and tissues [3, 4]. Hence, it is significant to develop methods to enhance the corrosion
* Ramalingam Manonmani [email protected] 1
Department of Chemistry, Rajalakshmi Engineering College, Chennai 602105, India
resistance of such implants as well as making them bioactive so that new bone can be deposited. Hydroxyapatite [Ca10 (PO4)6 (OH)2] is one of the major important biocompatible ceramic materials which promotes osseointegration of implant materials to adjacent tissue because of its similar composition and structure to the human bone [5–8]. The nanoHAP has a strong ability to bond with proteins and bacteria which are present in our human body. Besides, nanoHAP also acts as filler because it repairs small holes and depressions on the damaged surface and
Data Loading...
