Descemet Membrane Endothelial Keratoplasty in Asian Eyes
- PDF / 1,677,462 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 52 Downloads / 189 Views
CORNEA (T YAMAGUCHI, SECTION EDITOR)
Descemet Membrane Endothelial Keratoplasty in Asian Eyes Toshiki Shimizu 1,2 & Satoru Yamagami 1 & Nobuhisa Mizuki 2 & Takahiko Hayashi 2,3 Accepted: 11 September 2020 # Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Purpose of Review Descemet membrane endothelial keratoplasty (DMEK) has become the treatment of choice for endothelial diseases such as Fuchs endothelial corneal dystrophy (FECD), especially in the United States and Europe. In this review, we give an overview of current knowledge about DMEK in Asian eyes and describe novel surgical modifications of this technique for these cases. Recent Findings Although many scientific reviews about DMEK in Caucasian eyes have already been published, there is still little knowledge about clinical outcomes of DMEK in Asian eyes. This is of particular importance, as there are substantial differences between DMEK in Asian and Caucasian eyes. Bullous keratopathy is the main indication for endothelial keratoplasty in Asia, whereas it is FECD in Caucasian countries. Considering etiological and anatomical differences, we have adapted DMEK for Asian eyes and have developed several technical modifications to improve clinical outcome. Summary Our work might be helpful in performing successful DMEK in the Asian setting. Keywords Descemet membrane endothelial keratoplasty . DMEK . Asian . Ethnical difference
Introduction Endothelial keratoplasty (EK) has been widely applied for corneal endothelial dysfunction such as Fuchs endothelial dystrophy (FECD) and bullous keratopathy (BK). There are two types of EK: Descemet stripping automated endothelial keratoplasty (DSAEK), the graft of which consists of thin stroma, Descemet This article is part of the Topical Collection on Cornea * Takahiko Hayashi [email protected] Toshiki Shimizu [email protected] Satoru Yamagami [email protected] Nobuhisa Mizuki [email protected] 1
Department of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Itabashi, Tokyo, Japan
2
Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
3
Department of Ophthalmology, Yokohama Minami Kyosai Hospital, Mutsuurahigashi 1-21-1, Kanazawa-ku, Yokohama city, Kanagawa 236-0037, Japan
membrane (DM), and the endothelial cell layer, and Descemet membrane endothelial keratoplasty (DMEK), where only the DM and the endothelial cell layer are replaced without a stromal lamella. Compared with penetrating keratoplasty (PK), DSAEK and DMEK have several advantages, including lower risk of intraoperative choroidal hemorrhage (no “open-sky surgery”), lower infection rates, lower graft rejection rates, faster visual recovery, less corneal denervation, and less postoperative astigmatism or higher-order aberrations [1]. DMEK compared with DSAEK has even lower graft rejection rates, faster visual recovery, smaller refractive changes, and better final visual acuity [2–6]. Due to these advantages, surgica
Data Loading...
