Design of Experiments and Advanced Statistical Techniques in Clinical Research
Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses
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Design of Experiments and Advanced Statistical Techniques in Clinical Research
Basavarajaiah D. M. Bhamidipati Narasimha Murthy
Design of Experiments and Advanced Statistical Techniques in Clinical Research
Basavarajaiah D. M. Karnataka Veterinary, Animal and Fisheries Sciences University Karnataka India
Bhamidipati Narasimha Murthy National Health Mission, Govt. of India National Institute of Epidemiology Chennai India
ISBN 978-981-15-8209-7 ISBN 978-981-15-8210-3 (eBook) https://doi.org/10.1007/978-981-15-8210-3 © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
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Preface
Statistics is the grammar of science and unique among the academic disciplines, and statistical thought is needed at every stages of research study almost all research investigations including planning, selecting the sample, managing the massive research data sets, and interpreting the resulted findings. Statistics is the science of learning from data and of measuring, controlling, and communicating uncertainty, providing a scientific navigational tools essential for taking appropriate clinical decisions at crucial times. Both clinical and statistical reasonings are very important to progress in medical research. The clinical research must infer from a few to many and combine evidence with several theory. Scientific discipline and study of empirical knowledge is generated from practical observations and ramification with research interest. Medical and statistica
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