Developmental Aspects of the Lymphatic Vascular System

For decades, lymphatic vessels were considered to be of “lesser significance” than blood vessels, and the fundamental importance of lymphatic vessels for physiological tissue homeostasis and their involvement in many pathological processes have only recen

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Friedemann Kiefer Stefan Schulte-Merker Editors

Developmental Aspects of the Lymphatic Vascular System

Reviews and critical articles covering the entire field of normal anatomy (cytology, histology, cyto- and histochemistry, electron microscopy, macroscopy, experimental morphology and embryology and comparative anatomy) are published in Advances in Anatomy, Embryology and Cell Biology. Papers dealing with anthropology and clinical morphology that aim to encourage cooperation between anatomy and related disciplines will also be accepted. Papers are normally commissioned. Originalpapers and communications may be submitted and will be considered for publication provided they meet the requirements of a review article and thus fit into the scope of “Advances”. English language is preferred. It is a fundamental condition that submitted manuscripts have not been and willnot simultaneously be submitted or published elsewhere. With the acceptance of a manuscript for publication, the publisher acquires full and exclusive copyright for all languages and countries. Twenty-five copies of each paper are supplied free of charge.

Manuscripts should be addressed to

Co-ordinating Editor Prof. Dr. H.-W. KORF , Zentrum der Morphologie, Universität Frankfurt, Theodor-Stern Kai 7, 60595 Frankfurt/Main, Germany e-mail: [email protected]

Editors Prof. Dr. F. BECK, Howard Florey Institute, University of Melbourne, Parkville, 3000 Melbourne, Victoria, Australia e-mail: [email protected] Prof. Dr. F. CLASCÁ, Department of Anatomy, Histology and Neurobiology Universidad Autónoma de Madrid, Ave. Arzobispo Morcillo s/n, 28029 Madrid, Spain e-mail: [email protected] Prof. Dr. D.E. HAINES, Ph.D., Department of Anatomy, The University of Mississippi Med. Ctr., 2500 North State Street, Jackson, MS 39216–4505, USA e-mail: [email protected] Prof. Dr. N. HIROKAWA, Department of Cell Biology and Anatomy, University of Tokyo, Hongo 7–3–1, 113-0033 Tokyo, Japan e-mail: [email protected] Dr. Z. KMIEC, Department of Histology and Immunology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland e-mail: [email protected] Prof. Dr. R. PUTZ, Anatomische Anstalt der Universität München, Lehrstuhl Anatomie I, Pettenkoferstr. 11, 80336 München, Germany e-mail: [email protected] Prof. Dr. J.-P. TIMMERMANS, Department of Veterinary Sciences, University of Antwerpen, Groenenborgerlaan 171, 2020 Antwerpen, Belgium e-mail: [email protected]

214 Advances in Anatomy, Embryology and Cell Biology

Co-ordinating Editor H.-W. Korf, Frankfurt

Series Editors F. Beck • F. Clasca´ • D.E. Haines • N. Hirokawa Z. Kmiec • R. Putz • J.-P. Timmermans For further volumes: http://www.springer.com/series/102

Friedemann Kiefer • Stefan Schulte-Merker Editors

Developmental Aspects of the Lymphatic Vascular System with 27 Figures

Editors Friedemann Kiefer MPI for Molecular Biomedicine Mu¨nster Germany

Stefan Schulte-Merker Hubrecht Institute Development Biology Utrecht The Netherlands

ISSN 0301-5556 ISSN 2192-