Diabetes in Women Pathophysiology and Therapy

Gender differences impact the pathophysiology and clinical burden of diabetes in women. Exploring the complex interplay between gender and diabetes, Diabetes in Women provides a state-of-the-art update from conception to menopause and

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Contemporary Diabetes Aristidis Veves, MD, DSc Series Editor The Diabetic Foot: Second Edition, edited by Aristidis Veves, md, John M. Giurini, dpm, and Frank W. LoGerfo, md, 2006 The Diabetic Kidney: edited by Pedro Cortes, md and Carl Erik Mogensen, md, 2006 Obesity and Diabetes: edited by Christos S. Mantzoros, md, 2006 Diabetic Retinopathy: edited by Elia J. Duh, md, 2008 Diabetes and Exercise: edited by Judith G. Regensteiner, phd, Jane E.B. Reusch, md, Kerry J. Stewart, edd, Aristidis Veves, md, dsc, 2009 Diabetes in Women: edited by Agathocles Tsatsoulis, md, phd, frcp, Jennifer Ann Wyckoff, md, Florence M. Brown, md, 2009

Diabetes in Women

Edited by

Agathocles Tsatsoulis, md, phd, frcp

Department of Endocrinology, University of Ioannina Medical School, Ioannia, Greece

Jennifer Wyckoff, md

Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

Florence M. Brown, md

Harvard Medical School, Department of Medicine, Joslin Diabetes Center, Boston, MA, USA

Editors Agathocles Tsatsoulis, md, phd, frcp Department of Endocrinology University of Ioannina Medical School Ioannia Greece

Jennifer Wyckoff, md Division of Endocrinology, Metabolism and Diabetes Department of Internal Medicine University of Michigan Ann Arbor, MI USA

Florence M. Brown, md Harvard Medical School Department of Medicine, Joslin Diabetes Center Boston, MA USA

ISBN 978-1-60327-249-0 e-ISBN 978-1-60327-250-6 DOI 10.1007/978-1-60327-250-6 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2009926313 © Humana Press, a part of Springer Science+Business Media, LLC 2009 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is for-bidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)



“The Book is dedicated to my wife Mary for her understanding and support, and to all women with Diabetes” Agathocles Tsatsoulis



“ I would like to dedicate this work to all my patients who are my inspiration and to my family who are my strength.” Jennifer Ann Wyckoff



“This book is dedicated to Suzanne Ghiloni, RN, CDE, and Breda Curran for their combined service of over 45 years to the Joslin Diabetes in Pregnancy Program.” Florence M. Brown

Preface

This book is devoted to women with diabetes and to women at risk of diabetes. The