Diagnosis of coarctation with MR using carotid-subclavian artery index
- PDF / 259,567 Bytes
- 3 Pages / 610 x 792 pts Page_size
- 61 Downloads / 170 Views
BioMed Central
Open Access
Poster presentation
Diagnosis of coarctation with MR using carotid-subclavian artery index Yu-Po Chen*, Aoife Keeling and James C Carr Address: Northwestern University Feinberg School of Medicine, Chicago, IL, USA * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P23
doi:10.1186/1532-429X-12-S1-P23
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/P23 © 2010 Chen et al; licensee BioMed Central Ltd.
Introduction Aortic coarctation is a common condition defined as the narrowing of the aorta, usually just distal to the origin of the left subclavian artery, and often associated with other conditions such as bicuspid aortic valve or ventricular spetal defect [1]. Dodge-Khatami, et al. introduced the use of carotid-subclavian artery index as an alternative way of predicting coarctation independent of other variables in neonates and infants [2]. The index's validity with modalities other than echocardiography and in adults has not been explored, however.
Purpose In this study, we test the hypothesis that the carotid-subclavian artery index can be used with MR in adults to predict the presence of aortic coarctation.
artery and the origin of the left subclavian artery (d2), the aortic arch diameter at the origin of the left carotid artery (d3), and the descending aorta diameter (d4). The carotid-subclavian artery index is defined as the ratio of d3 to d2.
Results The carotid-subclavian artery index is significantly smaller in the coarctation group compared to the control. The data suggest that a cutoff of 1.5 for using the carotid-subclavian artery index to diagnose coarctation provides the best sensitivity and specificity simultaneously. The area under the ROC curve is 0.955, suggesting that the carotidsubclavian artery index has excellent accuracy. See figures 1 and 2 and Tables 1, 2 and 3
Conclusion Methods Patients and controls were selected retrospectively from the database at NMH according to IRB-approved protocols. We identified and selected patients who had a diagnosis of aortic coarctation or history of coarctation repair and underwent contrast enhanced magnetic resonance angiography (CE-MRA) between 2006 and 2009. Patients with comparable age-distribution and normal MR images of their aortas were chosen from the same database as controls. The MR imaging protocol has been previously published [3]. For each subject, we measured the following aortic dimensions on user-defined multiplanar reformats (MPR) and thin MIPs: distance between the origin of the brachiocephalic trunk and the origin of the left carotid artery (d1), distance between the origin of the left carotid
We have demonstrated
Data Loading...
