Disposition of Oral Cannabidiol-Rich Cannabis Extracts in Children with Epilepsy
- PDF / 700,633 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 23 Downloads / 160 Views
ORIGINAL RESEARCH ARTICLE
Disposition of Oral Cannabidiol‑Rich Cannabis Extracts in Children with Epilepsy George Sam Wang1 · David W. A. Bourne2 · Jost Klawitter3 · Cristina Sempio3 · Kevin Chapman4 · Kelly Knupp4 · Michael F. Wempe2 · Laura Borgelt5 · Uwe Christians3 · Jan Leonard1 · Kennon Heard6 · Lalit Bajaj1
© Springer Nature Switzerland AG 2020
Abstract Background and Objectives Despite limited evidence, cannabidiol-rich cannabis extracts have been popularly used in pediatrics. With increased use, it is critical to determine basic pharmacokinetic parameters of cannabidiol in these extracts in the pediatric population. The objective of this study was to determine the disposition of oral cannabidiol cannabis extracts and drug interactions in children with pediatric epilepsy. Methods We conducted a prospective observational study evaluating the disposition of oral cannabidiol in children ( 24 months and
Data Loading...
