Drug Discovery from Mother Nature

Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases. Food and drug administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory dru

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Subash Chandra Gupta Sahdeo Prasad Bharat B. Aggarwal Editors

Drug Discovery from Mother Nature

Advances in Experimental Medicine and Biology Volume 929

Series editors Irun R. Cohen, Rehovot, Israel N.S. Abel Lajtha, Orangeburg, USA Rodolfo Paoletti, Milan, Italy John D. Lambris, Philadelphia, USA

More information about this series at http://www.springer.com/series/5584

Subash Chandra Gupta Sahdeo Prasad Bharat B. Aggarwal •

Editors

Drug Discovery from Mother Nature

123

Editors Subash Chandra Gupta Banaras Hindu University Varanasi, Uttar Pradesh India

Bharat B. Aggarwal Inflammation Research Institute San Diego, CA USA

Sahdeo Prasad MD Anderson Cancer Center University of Texas Houston, TX USA

ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-41341-9 ISBN 978-3-319-41342-6 (eBook) DOI 10.1007/978-3-319-41342-6 Library of Congress Control Number: 2016947753 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

Cinnamon and Chronic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mitra Hariri and Reza Ghiasvand

1

Silymarin and Its Role in Chronic Diseases . . . . . . . . . . . . . . . . . . . . . . . Neha, Amteshwar S. Jaggi and Nirmal Singh

25

Eugenol and Its Role in Chronic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . S. Fujisawa and Y. Murakami

45

Catechins and Its Role in Chronic Diseases . . . . . . . . . . . . . . . . . . . . . . . Yohei Shirakami, Hiroyasu Sakai, Takahiro Kochi, Mitsuru Seishima and Masahito Shimizu

67

Capsaicin and Its Role in Chronic Diseases . . . . . . . . . . . . . . . . . . . . . . . E.S. Fernandes, A.R.A. Cerqueira, A.G. Soares and Soraia K.P. Cost