Dual-energy CT angiography in suspected pulmonary embolism: influence of injection protocols on image quality and perfus
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ORIGINAL PAPER
Dual‑energy CT angiography in suspected pulmonary embolism: influence of injection protocols on image quality and perfused blood volume Aleksander Kosmala1 · Philipp Gruschwitz1 · Simon Veldhoen1 · Andreas Max Weng1 · Bernhard Krauss2 · Thorsten Alexander Bley1 · Bernhard Petritsch1 Received: 13 March 2020 / Accepted: 2 June 2020 © Springer Nature B.V. 2020
Abstract To compare intravenous contrast material (CM) injection protocols for dual-energy CT pulmonary angiography (CTPA) in patients with suspected acute pulmonary embolism with regard to image quality and pulmonary perfused blood volume (PBV) values. A total of 198 studies performed with four CM injection protocols varying in CM volume and iodine delivery rates (IDR) were retrospectively included: (A) 60 ml at 5 ml/s (IDR = 1.75gI/s), (B) 50 ml at 5 ml/s (IDR = 1.75gI/s), (C) 50 ml at 4 ml/s (IDR = 1.40gI/s), (D) 40 ml at 3 ml/s (IDR = 1.05gI/s). Image quality and PBV values at different resolution settings were compared. Pulmonary arterial tract attenuation was highest for protocol A (397 ± 110 HU; p vs. B = 0.13; vs. C = 0.02; vs. D
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