Early Diagnosis of Intraocular Hypertension: Ibopamine Test
The following provocation tests have been used in the past: water overload (water test), caffeine, Vasculat, Priscol, amyl nitrite, jugular compression, Valsalva maneuver, cycloplegic mydriatics, reading, darkness, cortisone.
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16.1
Contents 16.1 16.1.1
History....................................................... Provocation Test.........................................
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16.2
16.2.1 16.2.2 16.2.3
The Role of Ibopamine in the Pathophysiology of Intraocular Pressure and in the Early Diagnosis of Ocular Hypertension: Correlation with the Diurnal Pressure Curve (DPC) ............... Purpose....................................................... Results........................................................ Conclusion .................................................
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16.3 16.3.1
Introduction .............................................. Diurnal Pressure Curve ..............................
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16.4 16.4.1 16.4.2
Material and Methods ............................. Material ...................................................... Method .......................................................
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16.5 16.5.1
Results ....................................................... Statistical Processing and Analysis............
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16.6
Discussion .................................................
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16.7
Examples ...................................................
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16.8
Addendum ................................................
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References ...............................................................
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16
History
16.1.1 Provocation Test The following provocation tests have been used in the past: water overload (water test), caffeine, Vasculat, Priscol, amyl nitrite, jugular compression, Valsalva maneuver, cycloplegic mydriatics, reading, darkness, cortisone. Those wanting to enquire more deeply into each of these tests can refer to Ch. 51.4 of the book “La malattia glaucomatosa dalla semeiotica alla terapia” by Virno, Pecori Giraldi, Gregorio, and Taloni (2005). We have used all of these and they have not been useful for the early diagnosis of hypertension. For this reason, as we have seen in previous chapters, the best way of detecting increases in ocular hypertension has been the DPC, using the algorithm I developed. When I met Prof. Virno 8 years ago, he showed me his ibopamine test, and at first I doubted its effectiveness, as in the previous tests I have mentioned. We agreed that I should do a comparative study in comparing the results in different groups of patients of a DPC and the ibopamine test. The final conclusion was a great surprise for me, because after more than 40 years of using the diurnal pressure curve with applanation (DPC) from 6 a.m. with the patient in supine position, at bed, and then at 9 a.m., 12 p.m., 15 p.m., and 18 p.m. with the patient in the hospital seated at the slit lamp, with all the problems associated with carrying this out, I have nowadays replaced
R. Sampaolesi et al., The Glaucomas, DOI 10.1007/978-3-642-35500-4_16, © Springer-Verlag Berlin Heidelberg 2014
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Early Diagnosis of Intraocular Hypertension: Ibopamine Test
the DPC, from diagnostic point of view, by the ibopamine test, since this has the same value for the early
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