Effects of upright T-wave in lead aVR on left ventricular volume and function derived from ECG-gated SPECT in patients w

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ORIGINAL ARTICLE

Effects of upright T‑wave in lead aVR on left ventricular volume and function derived from ECG‑gated SPECT in patients with advanced chronic kidney disease Satoshi Kurisu1 · Kazuhiro Nitta1 · Noriaki Watanabe1 · Hiroki Ikenaga1 · Ken Ishibashi1 · Yukihiro Fukuda1 · Yukiko Nakano1 Received: 12 August 2020 / Accepted: 13 September 2020 © The Japanese Society of Nuclear Medicine 2020

Abstract Background  Numerous studies have shown the association between chronic kidney disease (CKD) and adverse cardiac events. We investigated whether or not the upright T-wave in lead aVR (TaVR) could predict left ventricular (LV) volume and function derived from ECG-gated SPECT in patients with advanced CKD. Methods  Two hundred and sixty-one patients with advanced CKD [estimated glomerular filtration rate (eGFR)  0 mV. Enlarged LV enddiastolic volume (LVEDV) was defined as LVEDV index of > 76 ml/m2 in men and > 57 ml/m2 in women. Reduced LV ejection fraction (LVEF) was defined as LVEF of