Impact of parathyroidectomy on left ventricular function in end stage renal disease patients
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RESEARCH ARTICLE
Open Access
Impact of parathyroidectomy on left ventricular function in end stage renal disease patients Shaohua Chen1,2, Kaixiang Sheng1,2, Ying Shen1,2, Hua Jiang1,2, Xin Lei1,2, Lihui Qu1,2, Chunping Xu1,2, Jianghua Chen1,2 and Ping Zhang1,2*
Abstract Background: Secondary hyperparathyroidism (SHPT) is a common complication in end-stage renal disease (ESRD) patients, and parathyroidectomy (PTX) is an effective treatment intervention of SHPT. However, the curative impact of PTX on left ventricular function still remains incompletely understood. To evaluate the impact of parathyroidectomy on left ventricular function in ESRD patients, we conducted this retrospective study. Methods: Between Oct 1, 2010 and Oct 1, 2016, ESRD patients presented with SHPT who underwent parathyroidectomy were enrolled. We retrospectively collected the ultrasonic cardiogram parameter pre- and 1-year post-PTX, and analyzed the influence factor for the overturn of left ventricular hypertrophy (LVH) and the improvement of ejection fraction% (EF%). Results: In all the patients (135), the main ultrasonic cardiogram parameter dramatically improved after PTX. Compared with pre-PTX, the left ventricular mass (LVM) (172.82 (135.90, 212.91) g vs. 192.76 (157.56, 237.97) g, p
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