Emerging Technologies for Use in the Study, Diagnosis, and Treatment of Patients with COVID-19
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Cellular and Molecular Bioengineering (Ó 2020) https://doi.org/10.1007/s12195-020-00629-w
COVID-19
Emerging Technologies for Use in the Study, Diagnosis, and Treatment of Patients with COVID-19 MARIA TSIKALA VAFEA, ELEFTHERIA ATALLA, JOANNA GEORGAKAS, FADI SHEHADEH, EVANGELIA K. MYLONA, MARKOS KALLIGEROS, and ELEFTHERIOS MYLONAKIS Infectious Diseases Division, Rhode Island Hospital, Warren Alpert Medical School of Brown University, 593 Eddy Street, POB, 3rd Floor, Suite 328/330, Providence, RI 02903, USA (Received 28 May 2020; accepted 18 June 2020) Associate Editor Michael R. King oversaw the review of this article.
Abstract Introduction—The COVID-19 pandemic has caused an unprecedented health and economic worldwide crisis. Innovative solutions are imperative given limited resources and immediate need for medical supplies, healthcare support and treatments. Aim—The purpose of this review is to summarize emerging technologies being implemented in the study, diagnosis, and treatment of COVID-19. Results—Key focus areas include the applications of artificial intelligence, the use of Big Data and Internet of Things, the importance of mathematical modeling for predictions, utilization of technology for community screening, the use of nanotechnology for treatment and vaccine development, the utility of telemedicine, the implementation of 3D-printing to manage new demands and the potential of robotics. Conclusion—The review concludes by highlighting the need for collaboration in the scientific community with open sharing of knowledge, tools, and expertise. Keywords—Artificial intelligence, Nanomedicine, Vaccines, Drug repurposing, Monoclonal antibodies, Mathematical modeling, Big Data, Internet of Things, Community screening, Telemedicine, Robots, 3D-printing.
ARDS CDC CNN CT GPS HA HIV IBM IoT IoMT MRI NHIA NIA NP PPE RBD S SEIR SIR UAV UV
Acute Respiratory Distress Syndrome Centers for Disease Control and Prevention Convolutional Neural Networks Computed Tomography Global Positioning System Hemagglutinin Human Immunodeficiency Virus Individual Based Models Internet of Things Internet of Medical Things Magnetic Resonance Imaging National Health Insurance Administration National Immigration Agency Nanoparticles Personal Protective Equipment Receptor Binding Domain Spike Susceptible-Exposed-Infected-Recovered Susceptible-Infected-Recovered Unmanned Aerial Vehicles Ultraviolet
ABBREVIATIONS 3D ACE AI
3-Dimensional Angiotensin-Converting Enzyme Artificial Intelligence
Address correspondence to Eleftherios Mylonakis, Infectious Diseases Division, Rhode Island Hospital, Warren Alpert Medical School of Brown University, 593 Eddy Street, POB, 3rd Floor, Suite 328/330, Providence, RI 02903, USA. Electronic mail: [email protected] Maria Tsikala Vafea and Eleftheria Atalla contributed equally to this work.
INTRODUCTION A novel coronavirus (SARS-CoV-2, causing the disease COVID-19), was first identified in the city of Wuhan, in Hubei Province, China in December 2019 and has rapidly spread across the globe.60 The COVID-19 pa
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