Neuroendocrine Tumours Diagnosis and Management
This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation, and molecular biology through to diagnostic imaging methods and therapeutic options, including the la
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Neuroendocrine Tumours
Suayib Yalcin • Kjell Öberg Editors
Neuroendocrine Tumours Diagnosis and Management
Editors Suayib Yalcin Department of Medical Oncology Hacettepe University Cancer Institute Ankara, Turkey
Kjell Öberg Department of Endocrine Oncology Uppsala University Hospital Uppsala, Sweden
ISBN 978-3-662-45214-1 ISBN 978-3-662-45215-8 DOI 10.1007/978-3-662-45215-8
(eBook)
Library of Congress Control Number: 2015941427 Springer Heidelberg New York Dordrecht London © Springer-Verlag Berlin Heidelberg 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer-Verlag GmbH Berlin Heidelberg is part of Springer Science+Business Media (www.springer.com)
Contents
1
Introduction to Neuroendocrine Tumours . . . . . . . . . . . . . . . . . . . . . . . . 1 Suayib Yalcin
2
History of Neuroendocrine Tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Paula Marincola and Eric H. Liu
3
Epidemiology of Neuroendocrine Tumors . . . . . . . . . . . . . . . . . . . . . . . 23 Saadettin Kilickap and Kadir Mutlu Hayran
4
Molecular Biology of Neuroendocrine Tumors . . . . . . . . . . . . . . . . . . . 35 Aldo Scarpa, Vincenzo Corbo, Stefano Barbi, Ivana Cataldo, and Matteo Fassan
5
Genetic Syndromes Associated with Neuroendocrine Tumours . . . . . . 51 Wouter W. de Herder and Gerlof D. Valk
6
Pathological Evaluation and Classification of Digestive Neuroendocrine Tumours . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Anne Couvelard
7
Circulating Biomarkers in Neuroendocrine Tumours. . . . . . . . . . . . . . 77 Kjell Öberg
8
Cross-Sectional Imaging of Neuroendocrine Tumours . . . . . . . . . . . . . 97 Shema Hameed, Mark Wills, and Andrea Rockall
9
Nuclear Medicine Imaging in Neuroendocrine Tumors . . . . . . . . . . . 131 Andreas Kjaer
10
Neuroendocrine Tumors of the Lung . . . . . . . . . . . . . . . . . . . . . . . . . . 143 Dan Granberg
11
Overview of Gastrointestinal Neuroendocrine Tumours . . .
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