Epicardial adipose tissue thickness assessed by cardiac magnetic resonance is an independent indicator for coronary arte
- PDF / 70,171 Bytes
- 1 Pages / 595.28 x 793.7 pts Page_size
- 64 Downloads / 216 Views
POSTER PRESENTATION
Open Access
Epicardial adipose tissue thickness assessed by cardiac magnetic resonance is an independent indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients Hee Yeong Kim*, Young Jin Kim, Byoung Wook Choi From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Background We investigated the association between epicardial adipose tissue (EAT) thickness and myocardial ischemia as well as coronary artery stenosis assessed by cardiovascular magnetic resonance (CMR) in asymptomatic type 2 diabetic patients. Methods A total of 100 type 2 diabetic subjects (51 men and 49 women; mean age: 56.4 ± 7.6 years) were enrolled. Silent myocardial ischemia by CMR was defined as an evidence of inducible ischemia or myocardial infarction and signal reduction or stenosis of ≥ 50% in the vessel diameter were used as the criteria for significant coronary artery stenosis on coronary MR angiography. Results EAT thickness was positively correlated with BMI, waist-to-hip ratio, systolic blood pressure, postprandial glucose, fasting/postprandial triglyceride, HbA1c level, and HOMA-IR. A total of 24 patients had significant coronary artery stenosis and 14 patients had silent myocardia ischemia in CMR (3 with silent myocardial infarction, 13 with inducible ischemia, 2 with both). EAT thickness was higher in patients who had significant stenosis; however, it was not different between the subjects with silent myocardial ischemia and the subjects with no evidence of silent myocardial ischemia in CMR (13.0 ± 2.6 mm vs. 11.5 ± 2.1 mm, p=0.01, 12.8 ± 2.1 vs. 11.7 ± 2.3 mm, p=0.11, respectively). In multivariate logistic
regression analysis, EAT thickness was an independent indicator for significant coronary artery stenosis after adjusting for traditional risk factors (OR 1.353, p=0.031).
Conclusions Increased EAT thickness assessed by CMR is an independent risk factor for significant coronary artery stenosis in asymptomatic type 2 diabetes; however, the thickness was not associated with silent myocardial ischemia. Funding None. Published: 1 February 2012
doi:10.1186/1532-429X-14-S1-P78 Cite this article as: Kim et al.: Epicardial adipose tissue thickness assessed by cardiac magnetic resonance is an independent indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients. Journal of Cardiovascular Magnetic Resonance 2012 14(Suppl 1):P78.
Department of Radiology, Severance Hospital, University College of Medicine, Seoul, Republic of Korea © 2012 Kim et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Data Loading...
