Epigenetics in Cardiac Disease
This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone
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Johannes Backs Timothy A. McKinsey Editors
Epigenetics in Cardiac Disease
Cardiac and Vascular Biology Editor-in-chief: Markus Hecker Inst. of Physiology & Pathophysiology, Heidelberg University, Heidelberg, Germany Series Editors: Johannes Backs Department of Molecular Cardiology and Epigenetics, Heidelberg University, Heidelberg, Germany Marc Freichel Institute of Pharmacology, Heidelberg University, Heidelberg, Germany Thomas Korff Inst. of Physiology & Pathophysiology, Heidelberg University, Heidelberg, Germany Dierk Thomas Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany
The book series gives an overview on all aspects of state-of-the-art research on the cardiovascular system in health and disease. Basic research aspects of medically relevant topics are covered and the latest advances and methods covering diverse disciplines as epigenetics, genetics, mechanobiology, platelet research or stem cell biology are featured. The book series is intended for researchers, experts and graduates, both basic and clinically oriented, that look for a carefully selected collection of high quality review articles on their respective field of expertise. More information about this series at http://www.springer.com/series/13128
Johannes Backs • Timothy A. McKinsey Editors
Epigenetics in Cardiac Disease
Editors Johannes Backs Department of Molecular Cardiology and Epigenetics University of Heidelberg Heidelberg Germany
Timothy A. McKinsey Department of Medicine Division of Cardiology University of Colorado Denver Aurora Colorado USA
ISSN 2509-7830 ISSN 2509-7849 (electronic) Cardiac and Vascular Biology ISBN 978-3-319-41455-3 ISBN 978-3-319-41457-7 (eBook) DOI 10.1007/978-3-319-41457-7 Library of Congress Control Number: 2016956704 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Sp
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