Essentials of Tissue Banking

Tissue banking is undergoing a paradigm shift. There are now a plethora of guidance and regulatory documents, in response to recent regulation. There is however, relatively little information on the scientific and technical principles on routine tissue ba

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George Galea Editor

Essentials of Tissue Banking

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Editor Dr. George Galea, MD, FRCP, FRC Path Scottish National Blood Transfusion Service Ellens Glen Road Edinburgh EH17 7QT United Kingdom [email protected]

ISBN 978-90-481-9141-3 e-ISBN 978-90-481-9142-0 DOI 10.1007/978-90-481-9142-0 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2010931445 © Springer Science+Business Media B.V. 2010 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

A paradigm shift is taking in raising standards on all aspects of tissue banking from procurement to processing, from storage to clinical usage. A number of monographs have appeared giving guidance on GMP and quality systems that should be adhered to. There are also good guidelines on the significance of the new regulations that have been enacted. However there is a significant lack of information on the scientific basis and rationale on why tissue banking practices have developed the way they have. Many of them have developed without much validation and have been in use for many years, copied from one tissue bank to another. There are some good articles on some scientific aspects of tissue banking practices, but they are in relatively old and in somewhat obscure journals. This book is intended to fill this gap by getting a series of eminent experts to each write a chapter or two on up to date tissue banking practices. Moreover in the modern world of tissue banking, safety and quality of tissues have taken an increasingly important role. In fact these activities form the basis of many licensure activities that relate to tissue establishments. An attempt has been made to cover these aspects as well. Although the legislation covers all types of cells, including stem cells, they have been deliberately omitted. The target audiences for stem cells are different and the set up is also generally quite different unlike cord blood, which is very similar to tissues and therefore included. In order to limit the size of the book to a manageable level the authors have been only asked to cover the basis of current practices, rather than future developments, such as embryonic cell developments, tissue engineering and gene therapy, which are more cellular therapies than tissue banking, per se. Courses conferring certificates and diplomas have just started to be provided by various professional bodies. This is important because tissue banking is becoming a distinct modality for scientists who want to work in the field. I believe such an audience would be very keen to use this book. Also any scient