Etanercept
- PDF / 141,157 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 42 Downloads / 167 Views
1
Etanercept Transient paresis of the laryngeal nerve?: case report A 53-year-old man, with a long history of psoriasis vulgaris, started receiving SC etanercept 25mg twice weekly for an acute skin exacerbation. After 15 weeks of treatment, he presented with hoarseness and was diagnosed with paresis of the right recurrent laryngeal nerve (RLN). Etanercept was discontinued. Thorough investigations ruled out all common causes of RLN paresis. Serological testing detected a stable cytomegalovirus titre of 1:320. He received treatment with corticosteroids, rheologic infusions and speech therapy and had complete recovery within 6 months. Author comment: It is "unclear if direct viral damage of the recurrent laryngeal nerve was responsible for the paresis or if the inhibition of [tumour necrosis factor]α by etanercept therapy had induced autoimmune mechanisms affecting the neuronal micro-environment. The authors suggest the reported case probably related to the latter." Fiala K, et al. Transient paresis of the right recurrent laryngeal nerve after treatment with etanercept for plaque-type psoriasis. European Journal of Dermatology 20: e818-819, No. 6, Dec 2010. Available from: URL: http:// 803048184 dx.doi.org/10.1684/ejd.2010.1052 - Austria
0114-9954/10/1335-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 22 Jan 2011 No. 1335
Data Loading...
