Evolution of the Protein Synthesis Machinery and Its Regulation
The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leadin
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lution of the Protein Synthesis Machinery and Its Regulation
Evolution of the Protein Synthesis Machinery and Its Regulation
Greco Hernández Rosemary Jagus •
Editors
Evolution of the Protein Synthesis Machinery and Its Regulation
123
Editors Greco Hernández Division of Basic Research National Institute of Cancer Mexico City Mexico
ISBN 978-3-319-39467-1 DOI 10.1007/978-3-319-39468-8
Rosemary Jagus Institute of Marine and Environmental Technology University of Maryland Center for Environmental Science Baltimore, MD USA
ISBN 978-3-319-39468-8
(eBook)
Library of Congress Control Number: 2016940795 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
Proteins are one of the elementary molecules of the biosphere. They catalyze the majority of life-sustaining reactions and play structural, transport, and regulatory roles in all living organisms. Protein synthesis or “translation” is the process of decoding the genetic information of a messenger RNA by the ribosome along with translation factors to synthesize a protein. Translation regulation allows organisms to (1) rapidly respond to a variety of stresses, sudden environmental changes, and nutritional deficiencies, (2) produce proteins in tissues and developmental processes where transcription is strongly limited, and (3) elicit asymmetric localization of proteins when and where required. Thus, translation is a fundamental process for gene expression in all forms of life and should have evolved ever since the beginning of life. The knowledge of basic processes and regulatory mechanisms of translation was established in the last five decades by the brilliant work of many scientists in different countries, mostly studying the bacteria Escherichia coli, human, mouse, rabbit, the budding yeast Saccharomyces cerevisia
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