miRNA Regulation of the Translational Machinery
The silencing of gene expression by small interfering RNAs has been recognized for only a relatively short time, but this has transformed our understanding of both transcriptional and post-transcriptional gene regulatory mechanisms. Multiple pathways culm
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Volumes Published in the Series Progress in Molecular and Subcellular Biology
Subseries: Marine Molecular Biotechnology
Volume 35 RNA Trafficking and Nuclear Structure Dynamics Ph. Jeanteur (Ed.)
Volume 37 Sponges (Porifera) W.E.G. Müller (Ed.)
Volume 36 Viruses and Apoptosis C. Alonso (Ed.) Volume 38 Epigenetics and Chromatin Ph. Jeanteur (Ed.) Volume 40 Developmental Biology of Neoplastic Growth A. Macieira-Coelho (Ed.) Volume 41 Molecular Basis of Symbiosis J. Overmann (Ed.) Volume 44 Alternative Splicing and Disease Ph. Jeanlevr (Ed.) Volume 45 Asymmetric Cell Division A. Macieira Coelho (Ed.) Volume 48 Centromere Ðurđica Ugarković (Ed.) Volume 49 Aestivation C.A. Navas and J.E. Carvalho (Eds.) Volume 50 miRNA Regulation of the Translational Machinery R.E. Rhoads (Ed.)
Volume 39 Echinodermata V. Matranga (Ed.) Volume 42 Antifouling Compounds N. Fusetani and A.S. Clare (Eds.) Volume 43 Molluscs G. Cimino and M. Gavagnin (Eds.) Volume 46 Marine Toxins as Research Tools N. Fusetani and W. Kem (Eds.) Volume 47 Biosilica in Evolution, Morphogenesis, and Nanobiotechnology W.E.G. Müller and M.A. Grachev (Eds.)
Robert E. Rhoads Editor
miRNA Regulation of the Translational Machinery
Editor Robert E. Rhoads Louisiana State University Health Sciences Center in Shreveport Department of Biochemistry and Molecular Biology 1501 Kings Highway Shreveport LA 71130-3932 USA [email protected]
ISSN 0079-6484 ISBN 978-3-642-03102-1 e-ISBN 978-3-642-03103-8 DOI 10.1007/978-3-642-03103-8 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2009931693 © Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: Boekhorst Design BV, The Netherlands Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
An odd and unexpected finding was reported by the laboratory of Richard Jorgensen in 1990: expression of extra copies of the gene encoding chalone synthase in petunias turned off the
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