Exercise training early after acute myocardial infarction reduces stress-induced hypoperfusion and improves left ventric
- PDF / 346,705 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 44 Downloads / 203 Views
ORIGINAL ARTICLE
Exercise training early after acute myocardial infarction reduces stress-induced hypoperfusion and improves left ventricular function Francesco Giallauria & Wanda Acampa & Francesca Ricci & Alessandra Vitelli & Giorgio Torella & Rosa Lucci & Giuseppina Del Prete & Emilia Zampella & Roberta Assante & Giuseppe Rengo & Dario Leosco & Alberto Cuocolo & Carlo Vigorito
Received: 26 July 2012 / Accepted: 7 November 2012 / Published online: 6 December 2012 # Springer-Verlag Berlin Heidelberg 2012
Abstract Purpose Exercise training might exert its beneficial effects on myocardial perfusion by inducing coronary vascular adaptations or enhancing collateralization. We evaluated whether long-term exercise-based cardiac rehabilitation started early after ST-elevation acute myocardial infarction (STEMI) improves myocardial perfusion and left ventricular (LV) function. Methods Forty-six patients with recent STEMI and residual inducible hypoperfusion were randomized into two groups: 25 enrolled in a 6-month outpatient exercisebased cardiac rehabilitation programme (group T) and 21 discharged with generic instructions for maintaining physical activity and correct lifestyle (group C). All patients underwent cardiopulmonary exercise test and dipyridamole rest gated myocardial perfusion single photon emission computed tomography within 1 week after STEMI and at 6-month follow-up. F. Giallauria : A. Vitelli : G. Torella : R. Lucci : G. Rengo : D. Leosco : C. Vigorito Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, Naples, Italy W. Acampa : A. Cuocolo Institute of Biostructures and Bioimages, National Council of Research, Naples, Italy F. Ricci : G. Del Prete SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy E. Zampella : R. Assante : A. Cuocolo (*) Department of Biomorphological and Functional Sciences, University of Naples Federico II, Naples, Italy e-mail: [email protected]
Results At follow-up, group T showed an improvement in peak oxygen consumption, oxygen pulse and in the slope of increase in ventilation over carbon dioxide output (all p< 0.01) associated with a reduction of stress-induced hypoperfusion (p
Data Loading...
