Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients
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ORIGINAL ARTICLE
Feasibility of computed tomography‑based assessment of skeletal muscle mass in hemodialysis patients Tomoaki Takata1 · Aki Motoe2 · Katsumi Tanida3 · Sosuke Taniguchi2 · Ayami Ida2 · Kentaro Yamada1 · Shintaro Hamada1 · Masaya Ogawa2 · Marie Yamamoto1 · Yukari Mae1 · Takuji Iyama1 · Munehiro Taniguchi3 · Akihisa Nakaoka2 · Hajime Isomoto1 Received: 11 June 2020 / Accepted: 18 September 2020 © Italian Society of Nephrology 2020
Abstract Background Sarcopenia is a major health issue especially in patients on maintenance hemodialysis. Low skeletal muscle mass is included in the diagnostic criteria for sarcopenia. The skeletal muscle mass is usually evaluated by modalities such as bioimpedance analysis (BIA) or dual-energy X-ray absorptiometry, however the assessment of skeletal muscle mass using computed tomography (CT) images has not been established. The purpose of the study was to investigate the feasibility of the assessment of skeletal muscle mass using CT images in hemodialysis patients. Methods Skeletal muscle mass index (SMI) was measured by BIA and psoas muscle index (PMI) was measured by crosssectional CT images in 131 patients. The relationship between SMI and PMI and the diagnostic ability of PMI for low muscle mass were evaluated. Furthermore, the patients were followed up and long-term survival in patients with low and high PMI were compared. Results PMI measured at the L3 vertebral level was strongly correlated with SMI (r = 0.597, p
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