Feasibility of ultrahigh field (7 Tesla) human cardiovascular magnetic resonance imaging to assess cardiac volumes and m
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ORAL PRESENTATION
Open Access
Feasibility of ultrahigh field (7 Tesla) human cardiovascular magnetic resonance imaging to assess cardiac volumes and mass validated against 1.5 T and 3T field strengths Joseph J Suttie1*, Lance DeLaBarre2, Alex Pitcher1, Pierre-Francois van de Moortele2, Sairia Dass1, Carl J Snyder2, Jane M Francis1, Greg J Metzger2, Peter Weale3, Kamil Ugurbil4, Matthew D Robson1, Stefan Neubauer1, Tommy Vaughan2 From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Introduction Ultrahigh (7T) cardiovascular magnetic resonance imaging (CMR) is an emerging field of clinical research because theoretically higher signal to noise offers potential benefits for imaging coronaries, perfusion and spectroscopy. We report the first comparison of CMR at 1.5 T, 3 T and 7 T
field strengths using steady state free precession (SSFP) and fast low angle shot (FLASH) cine sequences.
Methods Ten volunteers underwent retrospectively ECG gated CMR at 1.5 T, 3 T and 7 T using FLASH and SSFP
Figure 1 Horizontal long axis (HLA) cardiac images acquired at 1.5, 3 and 7 T using fast low angle shot (FLASH) and steady state free precession (SSFP) sequences in the same subject.
1 Unversity of Oxford, Oxford, UK Full list of author information is available at the end of the article
© 2011 Suttie et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Suttie et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):O45 http://jcmr-online.com/content/13/S1/O45
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Figure 2 Myocardial signal to noise (SNR) and blood to myocardial contrast to noise ratios (CNR) for SSFP and FLASH sequences at 1.5 Tesla (T), 3 T and 7 T field strengths.
sequences (Figure 1). B1 and B0 shimming, and frequency scouts were used to optimise image quality.
Results Cardiac volume and mass measurements were not significantly affected by field strength when using the same imaging sequence (P>0.05 for all parameters at 1.5 T, 3 T and 7 T). SSFP imaging returned larger end diastolic and end systolic volumes and smaller left ventricular masses than FLASH imaging at 7 T and at the lower field strengths (P
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