Food allergy and related risk factors in 2540 preschool children: an epidemiological survey in Guangdong Province, south
- PDF / 737,066 Bytes
- 7 Pages / 595.22 x 842 pts (A4) Page_size
- 53 Downloads / 181 Views
Food allergy and related risk factors in 2540 preschool children: an epidemiological survey in Guangdong Province, southern China Guang-Qiao Zeng, Jia-Ying Luo, Hui-Min Huang, Pei-Yan Zheng, Wen-Ting Luo, Ni-Li Wei, Bao-Qing Sun Guangzhou, China
Methods: A random cluster-sampling method was used to select 24 kindergartens from 12 cities in Guangdong Province. The parents or guardians of the children were requested to complete a questionnaire on general information and data regarding FA diagnosis and symptoms in the children and their first-degree relatives. Thereafter, the Chi-square test, multivariate regression analysis, and Spearman's rank-order correlation coefficient analysis were performed to identify statistically significant differences. Results: Analysis of 2540 valid questionnaires revealed an FA prevalence rate of 4%. Adverse food reactions were due to the consumption of shrimp (4.4%), crab (3.2%), mango (2.3%), cow's milk and dairy products (1.9%), and eggs (1.4%). Logistic regression analysis indicated that a history of FA and a history of allergic rhinitis in the first-degree relatives were the major factors leading to FA in children.
Author Affiliations: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Zeng GQ, Luo JY, Huang HM, Zheng PY, Luo WT, Wei NL, Sun BQ) Corresponding Author: Sun Bao-Qing, MD, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital, Guangzhou Medical University, 151 Yanjiang Road, Guangzhou 510120, China (Tel: +86-20-8306-2865; Fax: +86-20-8306-2729; Email: [email protected]) doi: 10.1007/s12519-015-0030-6 ©Children's Hospital, Zhejiang University School of Medicine, China and Springer-Verlag Berlin Heidelberg 2015. All rights reserved.
World J Pediatr, Vol 11 No 3 . August 15, 2015 . www.wjpch.com
Conclusions: The incidence of FA in children in Guangdong Province is higher than that commonly believed. An individual's genetic background is an important risk factor for FA. Hence, mitigation of the impact of lifestyle and environmental factors should be carefully considered to reduce the incidence of childhood FA. World J Pediatr 2015;11(3):219-225 Key words: allergic rhinitis; eczema; epidemiology; food allergy; questionnaire
Introduction
T
he incidence of allergies has been increasing worldwide in recent decades. [1] In these allergies, food allergy (FA) in children has become a global health concern in a context of the ever-evolving modern lifestyles and diet. [2] In the United States, about 5.9 million children have a history of FA, representing an increase of 18%[3-6] over the past decade. Of these children, nearly 40% have experienced FA-related events ranging from transient hypotension to life-threatening anaphylaxis.[7,8] Allergic reactions to food are among the common
Data Loading...
