Forest malaria in Cambodia: the occupational and spatial clustering of Plasmodium vivax and Plasmodium falciparum infect
- PDF / 3,357,060 Bytes
- 12 Pages / 595.276 x 790.866 pts Page_size
- 19 Downloads / 204 Views
Malaria Journal Open Access
RESEARCH
Forest malaria in Cambodia: the occupational and spatial clustering of Plasmodium vivax and Plasmodium falciparum infection risk in a cross‑sectional survey in Mondulkiri province, Cambodia Mirco Sandfort1,2* , Amélie Vantaux3, Saorin Kim3, Thomas Obadia1,4, Anaïs Pepey3, Soazic Gardais1, Nimol Khim3, Dysoley Lek5,6, Michael White1,7, Leanne J. Robinson7,8,9, Benoit Witkowski3† and Ivo Mueller1,7,8†
Abstract Background: After a marked reduction in malaria burden in Cambodia over the last decades, case numbers increased again in 2017–2018. In light of the national goal of malaria elimination by 2025, remaining pockets of high risk need to be well defined and strategies well-tailored to identify and target the persisting burden cost-effectively. This study presents species-specific prevalence estimates and risk stratification for a remote area in Cambodia. Methods: A cross-sectional survey was conducted in 17 villages in the high-incidence province Mondulkiri in the dry season (December 2017 to April 2018). 4200 randomly selected participants (2–80 years old) were tested for Plasmodium infection by PCR. Risk of infection was associated with questionnaire-derived covariates and spatially stratified based on household GPS coordinates. Results: The prevalence of PCR-detectable Plasmodium infection was 8.3% (349/4200) and was more than twice as high for Plasmodium vivax (6.4%, 268) than for Plasmodium falciparum (3.0%, 125, p
Data Loading...
