Foundations in Grammatical Evolution for Dynamic Environments
Dynamic environments abound, encompassing many real-world problems in fields as diverse as finance, engineering, biology and business. A vibrant research literature has emerged which takes inspiration from evolutionary processes to develop problem-solvers
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		    Definition A ratio of the physical radiation doses required to produce a given endpoint such as the percentage of cell killing between hypoxic conditions and normoxic conditions. This is LETdependent and for low LET radiation is in the range of 2.5–3.0 compared with 1.5–2.0 for fast neutrons.
 
 Cross-References ▶ Neutron Radiotherapy
 
 Oligodendrogliomas ▶ Spinal Canal Tumor
 
 Omentum FILIP T. TROICKI1, JAGANMOHAN POLI2 1 College of Medicine, Drexel University, Philadelphia, PA, USA 2 Department of Radiation Oncology, College of Medicine, Drexel University, Philadelphia, PA, USA
 
 Definition Large layer of fatty tissue connected to the stomach and the intestines.
 
 Cross-References ▶ Colon Cancer ▶ Ovarian Cancer ▶ Stomach Cancer
 
 Oligoastrocytoma ▶ Primary Intracranial Neoplasms
 
 Oncogene ▶ Proto-oncogene
 
 Oligodendroglioma ▶ Primary Intracranial Neoplasms
 
 Oncotype DX ▶ Microarray Analysis
 
 L.W. Brady, T.E. Yaeger (eds.), Encyclopedia of Radiation Oncology, DOI 10.1007/978-3-540-85516-3, # Springer-Verlag Berlin Heidelberg 2013
 
 566
 
 O
 
 Oophorectomy
 
 Oophorectomy CHRISTIN A. KNOWLTON1, MICHELLE KOLTON MACKAY2 1 Department of Radiation Oncology, Drexel University, Philadelphia, PA, USA 2 Department of Radiation Oncology, Marshfield Clinic, Marshfield, WI, USA
 
 Definition The surgical removal of an ovary or ovaries. This procedure can be done alone but is most frequently performed with a hysterectomy and salpingectomy in cases of ovarian cancer. Because the ovaries produce the majority of the body’s hormones including estrogen, removal of the ovaries is linked to development of menopausal signs and symptoms such as hot flashes, vaginal dryness, depression, heart disease, osteoporosis, and decreased libido.
 
 Cross-References ▶ Ovary
 
 Opportunistic Infections HEDVIG HRICAK1, OGUZ AKIN2, HEBERT ALBERTO VARGAS2 1 Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA 2 Body MRI, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
 
 however, presents an “opportunity” for the pathogen to infect.
 
 Cross-References ▶ AIDS ▶ Chemotherapy ▶ Human Immunodeficiency Virus (HIV) ▶ Imaging in Oncology
 
 Orchiectomy JOHANNES CLASSEN Department of Radiation Oncology, St. Vincentius-Kliniken Karlsruhe, Karlsruhe, Germany
 
 Definition Surgical removal of the testis.
 
 Cross-References ▶ Prostate ▶ Testes
 
 ORN THEODORE E. YAEGER Department Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
 
 Definition Bone necrosis resulting from exposure to high dose radiation.
 
 Definition Infections caused by pathogens (bacterial, viral, fungal, or protozoan) that usually do not cause disease in a healthy host, that is, one with a healthy immune system. A compromised immune system,
 
 Cross-References ▶ Osteoradionecrosis (also ORN or Osteonecrosis) ▶ Sarcoma ▶ Sarcomas of the Head and Neck
 
 Oro-Hypopharynx
 
 Oro-Hypopharynx VOLKER BUDACH, CARMEN STROMBERGER Department of Radiotherapy and Radiation Oncology, Charite´ - University Hospital Berlin, Berlin, Germany
 
 Description Nonsurgical trea		
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