From Innate Immunity to Immunological Memory
The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination r
- PDF / 3,201,161 Bytes
- 189 Pages / 439.378 x 666.139 pts Page_size
- 97 Downloads / 205 Views
Editors R.W. Compans, Atlanta/Georgia M.D. Cooper, Birmingham/Alabama T. Honjo, Kyoto · H. Koprowski, Philadelphia/Pennsylvania F. Melchers, Basel · M.B.A. Oldstone, La Jolla/California S. Olsnes, Oslo · C. Svanborg, Lund P.K. Vogt, La Jolla/California · H. Wagner, Munich
B. Pulendran and R. Ahmed (Eds.)
From Innate Immunity to Immunological Memory
With 13 Figures and 6 Tables
123
Bali Pulendran, Ph.D. Rafi Ahmed, Ph.D. Emory Vaccine Center 954 Gatewood Road Atlante, GA 30329 USA e-mail: [email protected] [email protected]
Cover Illustration: The two intravital multi-photon micrographs show Ag-presenting dendritic cells (DCs) interacting with TCR transgenic T cells in a popliteal lymph node (LN) of an anesthetized mouse. In the background image the DCs (which were injected in the animal’s footpad one day earlier) are shown in red and CD4 and CD8 T cells are labeled in blue and green, respectively. In the smaller foreground image, a meshwork of LN-resident endogenous DCs are shown, which express chimeric MHC class II linked to GFP (green). CD4 T cells were labeled in red and interstitial collagen fibers are blue. Both images were generated in Dr. Ulrich H. von Andrian’s lab by Dr. Thorsten Mempel.
Library of Congress Catalog Number 72-152360 ISSN 0070-217X ISBN-10 3-540-32635-9 Springer Berlin Heidelberg New York ISBN-13 978-3-540-32635-7 Springer Berlin Heidelberg New York This work is subject to copyright. All rights reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September, 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springeronline.com © Springer-Verlag Berlin Heidelberg 2006 The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Editor: Simon Rallison, Heidelberg Desk editor: Anne Clauss, Heidelberg Production editor: Nadja Kroke, Leipzig Cover design: WMXDesign, Heidelberg Typesetting: LE-TEX Jelonek, Schmidt & Vöckler GbR, Leipzig Printed on acid-free paper SPIN 11679127 27/3150/YL – 5 4 3 2 1 0
From Innate Immunity to Immunological Memory
The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the
Data Loading...
