Crossroads between Innate and Adaptive Immunity

This compilation presents minireviews derived from work presented at the - gean Conference: “First Crossroads between Innate and Adaptive Immunity,” which occurred October 9–14, 2005 at the Hilton Conference Center on the - land of Rhodes, Greece. The con

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan Recent Volumes in this Series Volume 582 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN III Edited by Andrew J. Pollard and Adam Finn Volume 583 TAURINE 6 Edited by Simo S. Oja and Pirjo Saransaari Volume 584 LYMPHOCYTE SIGNAL TRANSDUCTION Edited by Constantine Tsoukas Volume 585 TISSUE ENGINEERING Edited by John P. Fisher Volume 586 CURRENT TOPICS IN COMPLEMENT Edited by John D. Lambris Volume 587 NEW TRENDS IN CANCER FOR THE 21st CENTURY Edited by Antonio Llombart-Bosch, Jose López-Guerrero and Vincenzo Felipe Volume 588 HYPOXIA AND EXERCISE Edited by Robert C. Roach, Peter D. Wagner, and Peter H. Hackett Volume 589 NEURAL CREST INDUCTION AND DIFFERENTIATION Edited by Jean-Pierre Saint-Jeannet Volume 590 CROSSROADS BETWEEN INNATE AND ADAPTIVE IMMUNITY Edited by Peter D. Katsikis, Bali Pulendran and Stephen P. Schoenberger A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Peter D. Katsikis Bali Pulendran Stephen P. Schoenberger Editors

Crossroads between Innate and Adaptive Immunity With 39 Illustrations

Peter D. Katsikis Drexel University College of Medicine Philadelphia, Pennsylvania USA [email protected]

Stephen P. Schoenberger La Jolla Institute for Allergy and Immunology La Jolla, California USA [email protected]

Bali Pulendran Emory University Emory Vaccine Center Atlanta, Georgia USA [email protected]

Library of Congress Control Number: 2006931119 Printed on acid-free paper. ISBN-10: 0-387-34813-1 ISBN-13: 978-0387-34813-1

e-ISBN-10: 0-387-34814-X e-ISBN-13: 978-0387-34814-8

Proceedings of the “First Crossroads between Innate and Adaptive Immunity” Conference, held in Rhodes, Greece, October 9-14, 2005. © 2007 Springer Science+Business Media, LLC All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. 9 8 7 6 5 4 3 2 1 springer.com

Preface

This compilation presents minireviews derived from work presented at the Aegean Conference: “First C