Genetic Disorders Among Arab Populations

Arab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions

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Ahmad S. Teebi Editor

Genetic Disorders Among Arab Populations Second Edition

Editor Ahmad S. Teebi Weill Cornell Medical College in Qatar Qatar Foundation Doha Education City Qatar [email protected]

First edition published by Oxford University Press, 1997. ISBN 978-3-642-05079-4 e-ISBN 978-3-642-05080-0 DOI 10.1007/978-3-642-05080-0 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2010932676 # Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMXDesign GmbH, Heidelberg, Germany Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

To my parents, brothers and sisters, and my children Saeed, Basel, Asil and Asma and the whole Arab Family.

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Acknowledgements

The editor is grateful to the authors of the individual chapters who welcomed the initiative and were keen to provide their contributions on time. Special thanks to Professor Charles R. Scriver, who made the effort to write the foreword to this book. I am thankful to my wife Mrs. Amal Teebi for her encouragement and support and to Saeed Teebi for his assistance in some parts of the manuscript. The assistance of Mrs. Mariette D’ Souza, Gemma Fabricante and Martin Marion from Weill Cornell Medical College in Qatar, in preparation of some chapters and maps, is greatly appreciated. I express my gratitude also to Springer press and in particular to Andrea Pillman and Ursula Gramm for their help in the publication of this book.

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Foreword

Genetic Disorders among Arab Populations by Ahmad S. Teebi and co-authors appears here in its second edition. The first edition (in 1997) shows how one could tap into a rich load of information on human and medical genetics, a source probably too little mined until now. One can be pleased that the first edition was warmly welcomed by Prof. Victor McKusick, the author of the Foreword to that edition. The authors of this edition have taken pains to remind us again that persons and patients, and the corresponding families and communities, represent a stream of human history and a region of the world that embraces ethnic, cultural and religious attributes more diverse than we might have