Glucocrinology of Modern Sulfonylureas: Clinical Evidence and Practice-Based Opinion from an International Expert Group
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Glucocrinology of Modern Sulfonylureas: Clinical Evidence and Practice-Based Opinion from an International Expert Group Sanjay Kalra . A. K. Das . M. P. Baruah . A. G. Unnikrishnan . Arundhati Dasgupta . Parag Shah . Rakesh Sahay . Rishi Shukla. Sambit Das . Mangesh Tiwaskar . G. Vijayakumar . Manoj Chawla . Fatimah Eliana . Ketut Suastika . Abbas Orabi. Aly Ahmed Abdul Rahim . Andrew Uloko . Silver Bahendeka . Abdurezak Ahmed Abdela . Fariduddin Mohammed . Faruque Pathan . Muhammed Hafizur Rahman . Faria Afsana . Shajada Selim . Muaz Moosa. Moosa Murad . Pradeep Krishna Shreshtha . Dina Shreshtha . Mimi Giri . Wiam Hussain . Ahmed Al-Ani. Kaushik Ramaiya . Surender Singh . Syed Abbas Raza . Than Than Aye . Chaminda Garusinghe . Dimuthu Muthukuda. Muditha Weerakkody . Shyaminda Kahandawa . Charlotte Bavuma . Sundeep Ruder . Koy Vanny. Manish Khanolkar . Leszek Czupryniak Received: February 23, 2019 The Author(s) 2019
Electronic Supplementary Material The online version of this article (https://doi.org/10.1007/s13300019-0651-1) contains supplementary material, which is available to authorized users.
Background: Modern SUs may be considered a panacea in DM care with their beneficial extrapancreatic, pleiotropic, and cardiovascular effects. Safe glycemic control with SUs could be achieved with appropriate patient selection, drug and dosage selection, and patient empowerment. Additionally, sulfonylureas also exhibit certain endocrine and metabolic effects, which could be considered beneficial in the management of DM. In this regard, a group of international clinical experts discussed the less known beneficial aspects of SUs and safe and smart prescription of modern SUs in DM care. Results: The concept of glucocrinology or the relationship of glycemia with the endocrine system was emphasized during the meetings. Clinical experts arrived at a consensus for the
S. Kalra (&) Department of Endocrinology, Bharti Hospital and BRIDE, Karnal, Haryana, India e-mail: [email protected]
A. G. Unnikrishnan Department of Endocrinology and Diabetes, Chellaram Diabetes Institute, Pune, Maharashtra, India
A. K. Das Department of Endocrinology and Medicine, Pondicherry Institute of Medical Sciences, Puducherry, India
A. Dasgupta Department of Endocrinology, Rudraksh Superspecialty Care, Siliguri, India
ABSTRACT Aim: The primary objective of this document is to develop practice-based expert group opinion on certain important but less discussed endocrine and metabolic effects of modern sulfonylureas (SUs) and their usage in the management of diabetes mellitus (DM).
Enhanced Digital Features To view enhanced digital features for this article go to https://doi.org/10.6084/ m9.figshare.8263688.
M. P. Baruah Department of Endocrinology, Excel Hospital, Guwahati, Assam, India
P. Shah Department of Endocrinology and Diabetes, Gujarat Endocrine Centre, Ahmedabad, India
Diabetes Ther
usage of modern SUs in the presence of other endocrine dysfunction and the impact of these drugs on endocrine health. The beneficial pleiotrop
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